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How High Is Breakthrough Infection Risk for People With Arthritis, HIV?

Among immunocompromised individuals vaccinated against COVID-19, solid organ transplant recipients as well as those with HIV and rheumatoid arthritis (RA) were significantly more likely to experience breakthrough infections versus people without immune dysfunction, a retrospective study found. In a national database analysis involving over 650,000 people who received at least one vaccine dose, the highest […]

Study: Drug Use a Factor in COVID Breakthrough Infections

Fully vaccinated individuals with substance use disorders were more likely to have breakthrough COVID-19 infections than those without such disorders, researchers found. Adjusted analyses found that breakthrough infections were higher in patients with all types of substance use disorder, except tobacco, and were the highest among cocaine users (HR 2.06, 95% CI 1.30-3.25) and cannabis […]

Certain Groups Left Behind in HIV Preventive Care

Black and Hispanic individuals at risk for HIV, as well as young adults and people with substance use disorder (SUD), were more likely to experience gaps in preexposure prophylaxis (PrEP) care, a retrospective study showed. Examining electronic health record (EHR) data of people linked to PrEP care from 2012 to 2019, Black (HR 0.74, 95% […]

Survivors of trauma struggle to move on from the loss of loved ones: Treating post-traumatic stress symptoms early could prevent persistent grief later, study finds

Among individuals who survive a trauma that resulted in the loss of a close friend or loved one, symptoms of post-traumatic stress disorder can predict complicated grief — a sense of persistent sadness and an inability to cope — years after the trauma, according to research published by the American Psychological Association. “Grief is a […]

Drug Resistance in People on PrEP Who Acquire HIV

While a small subset of individuals acquired HIV despite being in a pre-exposure prophylaxis (PrEP) program, many of those people had mutations resistant to antiretroviral drugs, according to a study from the Global Evaluation of Microbicide Sensitivity (GEMS) project. Breakthrough HIV infections occurred in 204 individuals in GEMS, out of more than 104,000 people in […]

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