Testosterone Loss in Older Men: Factors Beyond Age in the Mix
Numerous factors — including body mass index (BMI), lifestyle, relationship status, and a number of disease states — were tied with declining testosterone levels in men over 70, researchers found. In a meta-analysis including about 25,000 men, testosterone levels were fairly stable from ages 17 to 70, but then started to significantly drop after that […]
Higher BMI = Less Neutropenia With CDK4/6 Inhibitor for Early Breast Cancer
A higher body mass index (BMI) translated into less neutropenia and fewer discontinuations among women with early hormone receptor (HR)-positive breast cancer treated with a CDK4/6 inhibitor, a secondary analysis of the randomized trial PALLAS showed. Among patients who received palbociclib (Ibrance) in addition to endocrine therapy, increasing BMI was associated with a small but […]
‘Overweight’ BMI Not Tied to Higher Risk of Death, U.S. Data Suggest
A body mass index (BMI) in the overweight — but not obese — range was not independently associated with an increased mortality risk, a retrospective study relying on two decades’ worth of National Health Interview Survey (NHIS) data found. Of roughly half a million U.S. adults captured in the 1999-2018 surveys, a slightly lower risk […]
Long COVID Cognitive, Depressive Symptoms Tied to Brain Inflammation Marker
An index of gliosis was linked with persistent neurocognitive symptoms after mild or moderate SARS-CoV-2 infection, a small case-control study showed. Compared with healthy controls, PET measures of translocator protein total distribution volume (TSPO VT), a marker of gliosis, was elevated in people with ongoing cognitive and depressive symptoms after COVID-19 (mean percentage difference 17%), […]
Higher BMI Tied to Other Severe Respiratory Infections Too
A higher body mass index (BMI) was associated with increased risks for hospitalization and death due to COVID-19 and other respiratory infections as well, according to a study using data from the U.K. Biobank. After a mean follow-up of 11.8 years, the hazard ratios per 10-unit higher BMI was 2.26 (95% CI 2.05-2.49) for severe […]
Child body weight has limited effects on mood and behavioral disorders
Childhood body mass index is unlikely to have a big impact on children’s mood or behavioural disorders, according to a study published today in eLife. The results suggest that some previous studies, which have shown a strong link between childhood obesity and mental health, may not have fully accounted for family genetics and environmental factors. […]
Mediterranean diet associated with a lower risk of mortality in older adults
A greater adherence to the Mediterranean diet which had been assessed through an index made with biomarkers during a 20-year scientific monitoring is associated with a lower mortality in adults over 65. This is one of the main conclusions of a study led by Cristina Andrés-Lacueva, head of the Research Group on Biomarkers and Nutritional […]
Study finds body mass index for children greatest in Midwest, least in West
A study examining the body mass index (BMI) of over 14,000 children from birth to age 15 shows those in the Midwest have the highest BMI levels while kids in the West have the lowest, suggesting regional influences may play a role in the development of childhood obesity. The study, published today in the journal […]