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Iodine Linked With Men’s Testosterone Levels

Lower iodine concentrations in the urine was independently associated with higher testosterone levels, a cross-sectional study found. Looking at nearly 3,000 U.S. men, those with lower urinary iodine concentrations had significantly higher total testosterone levels than men with either normal or high iodine levels (β -0.028, 95% CI -0.049 to -0.006, P=0.01), Arcangelo Barbonetti, PhD, […]

Some NSCLC Patients on ICI Therapy Fare Worse With Proton Pump Inhibitor Use

Proton pump inhibitor (PPI) use was independently associated with worse treatment outcomes in some patients with non-small cell lung cancer (NSCLC) on immune checkpoint inhibitor (ICI) therapy with pembrolizumab (Keytruda), according to a Japanese multicenter cohort study. Among patients with a PD-L1 tumor proportion score (TPS) of 50% or more, a history of PPI use […]

‘Overweight’ BMI Not Tied to Higher Risk of Death, U.S. Data Suggest

A body mass index (BMI) in the overweight — but not obese — range was not independently associated with an increased mortality risk, a retrospective study relying on two decades’ worth of National Health Interview Survey (NHIS) data found. Of roughly half a million U.S. adults captured in the 1999-2018 surveys, a slightly lower risk […]

Study links nutrients, brain structure, cognition in healthy aging

In a new study, scientists explored the links between three measures known to independently predict healthy aging: nutrient intake, brain structure and cognitive function. Their analysis adds to the evidence that these factors jointly contribute to brain health in older adults. Reported in the Journal of Nutrition, the study found that blood markers of two […]

Opinion | A Bold U.K. Plan to End the Smoking Epidemic

A new report, independently commissioned by the Secretary of State for Health and Social Care of the U.K., provides cutting-edge recommendations with the aim of achieving a “Smokefree 2030.” This reflects the U.K. government’s ambition to reduce the smoking rate from 13.5% to 5% by the end of this decade. Authored by Javed Khan OBE, […]

Poor diet associated with increased diabetes risk across all gradients of genetic risk: A poor diet, irrespective of genetic risk factors, is associated with a 30 percent increased risk of diabetes

Genetic risk factors and diet quality are independently associated with type 2 diabetes; a healthy diet is linked to lower diabetes risk across all levels of genetic risk. That’s the conclusion of a study of more than 35,000 US adults publishing April 26 in PLOS Medicine by Jordi Merino of Massachusetts General Hospital, US, and […]

HIV Independently Tied to More Severe COVID-19

HIV was independently associated with a higher risk for severe or critical COVID-19, according to a World Health Organization (WHO) analysis. In a study of people living with HIV in Asia, Europe, Africa, and South America who also were hospitalized for COVID-19, HIV infection was linked with an increased risk of severe or critical COVID-19 […]

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