AI-Aided Colonoscopy Flops for Advanced Neoplasia Detection in Trial
Incorporating artificial intelligence (AI) computer-aided detection systems (CADe) into colonoscopy does not improve rates of advanced neoplasia detection, according to two studies in Annals of Internal Medicine. In the randomized CADILLAC trial of patients with a positive fecal immunochemical test, detection of advanced colorectal neoplasia was virtually identical with or without the use of CADe […]
FLT3 Inhibitor Doubles Overall Survival in Acute Myeloid Leukemia
Incorporating quizartinib into standard treatment for newly diagnosed acute myeloid leukemia (AML) followed by maintenance therapy with the investigational FLT3 inhibitor improved survival for patients with internal-tandem-duplication (ITD) mutations of FLT3, a placebo-controlled randomized trial showed. In the phase III study of over 500 patients undergoing standard induction and consolidation therapy, median overall survival (OS) […]
In the NICU, High-Flow Oxygen Boosts Intubation Success on First Attempt
Incorporating nasal high-flow therapy during endotracheal intubation attempts in the neonatal intensive care unit (NICU) increased the chance of success on the first try, a randomized study found. In the SHINE trial of just over 250 intubation attempts at a pair of Australian NICUs, 50% of those that included high-flow therapy had a successful first […]
Energy efficiency instead of long-term storage
Incorporating energy efficiency measures can reduce the amount of storage needed to power the nation’s buildings entirely with renewable energy, according to analysis conducted by researchers at the U.S. Department of Energy’s (DOE’s) National Renewable Energy Laboratory (NREL). As more communities plan to eventually rely on 100% renewable energy, the researchers offer a strategy that […]