Immunotherapy May Hold Promise for Skin Cancers After Kidney Transplant
The use of immune checkpoint inhibitors given as part of an immunosuppressive regimen for kidney transplant recipients with advanced cutaneous cancers may be effective and safe, depending on the regimen, two small studies suggested. In the first study among 12 kidney transplant recipients with advanced cutaneous squamous cell carcinoma (CSCC) who were treated with cemiplimab […]
Bacteria in donor organs complicate immune response after transplantation
Organ transplant recipients take life-long immunosuppressive drugs to prevent their bodies from mounting an immune response against the donated organ, yet a substantial number of them still reject the organs. A new study by researchers from the University of Chicago shows that transplant recipients also mount an immune response against commensal bacteria in the organ […]
Some IBD Treatments in Pregnancy Had No Effect on Kids’ Infection Risk
Exposure to immunosuppressive monotherapies in utero did not increase serious infection risks in young children born to mothers with inflammatory bowel disease (IBD), but the same could not be said for exposures to combination therapies, a French population-based study found. Children up to 1 year of age who were exposed to tumor necrosis factor (TNF) […]