Direct-to-Consumer Lab Tests Raise Ethical Questions, Researchers Say
Direct-to-consumer (DTC) laboratory tests — for the thyroid, hormonal biomarkers, or diabetes and hemoglobin A1c, for example — often had unclear terms of sale and vague privacy policies, a qualitative study showed. Of 21 U.S. companies that offered DTC lab tests, less than half declared compliance with the Health Insurance Portability and Accountability Act (HIPAA), […]
Another Link Between Prostate Cancer Hormone Tx and Impaired Cognition
Hormonal therapy for advanced prostate cancer, particularly enzalutamide (Xtandi), had a significant association with cognitive impairment, an analysis of a large drug-safety database showed. Traditional hormonal therapy increased the odds of cognitive impairment by 47% versus men who did not receive the therapy. The odds more than doubled among men who received novel androgen receptor […]
Combo Treatment Extends Survival in HR+HER2- Advanced Breast Cancer
Adding the CDK 4/6 inhibitor ribociclib (Kisqali) to a first-line hormonal treatment prolonged survival by more than 1 year in postmenopausal women with HR-positive/HER2-negative (HR+HER2-) advanced breast cancer, according to results from the MONALEESA-2 trial. Final overall survival (OS) results showed that patients treated with ribociclib plus the aromatase inhibitor (AI) letrozole (Femara) achieved a […]