New reasons eating less fat should be one of your resolutions
A UC Riverside study to motivate your new year’s resolutions: it demonstrates that high-fat diets affect genes linked not only to obesity, colon cancer and irritable bowels, but also to the immune system, brain function, and potentially COVID-19 risk. While other studies have examined the effects of a high-fat diet, this one is unusual in […]
How a high fat diet allows expulsion of intestinal parasite worms
Scientists have discovered that a high-fat diet allows the immune system to eliminate a parasitic worm which is a major cause of death and illness in the developing world. Parasitic worms affect up to a billion people, particularly in developing nations with poor sanitation. One of these parasites known as “whipworm” can cause long lasting […]
High-fat diets trigger inflammatory immune cell generation in bone: A study suggests that high-fat diets fuel the creation of inflammatory immune cells in the bone marrow of mice.
The results may help explain how high-fat diets trigger inflammation, which can contribute to the development of insulin resistance, type 2 diabetes and other complications in individuals with obesity. An invasion of inflammatory immune cells, called monocytes, into fat tissue is a hallmark of obesity, but what leads to this harmful phenomenon is unclear. Many […]
Can weekly prednisone treat obesity? Obese mice gain muscle mass and lose fat with once weekly prednisone
Obese mice that were fed a high-fat diet and that received prednisone one time per week had improved exercise endurance, got stronger, increased their lean body mass and lost weight, reports a new Northwestern Medicine study. The mice also had increased muscle metabolism. The once-weekly prednisone promoted nutrient uptake into the muscles. Investigators also found […]
A new study relates liquid fructose intake to fatty liver disease
A high-fat diet is not enough to cause short-term fatty liver disease. However, if this diet is combined with the intake of beverages sweetened with liquid fructose, the accumulation of fats in the liver accelerates and hypertriglyceridemia — a cardiovascular risk factor — can appear. This is explained in a study on a mouse experimental […]
How high-fat diets allow cancer cells to go unnoticed
A high-fat diet increases the incidence of colorectal cancer. Cold Spring Harbor Laboratory Fellow Semir Beyaz and collaborators from Harvard Medical School and Massachusetts Institute of Technology have discovered that in mice, fat disrupts the relationship between intestinal cells and the immune cells that patrol them looking for emerging tumors. Reconfiguring the gut microbiome may […]
Study reveals missing link between high-fat diet, microbiota and heart disease
A high-fat diet disrupts the biology of the gut’s inner lining and its microbial communities — and promotes the production of a metabolite that may contribute to heart disease, according to a study published Aug. 13 in the journal Science. The discoveries in animal models support a key role for the intestines and microbiota in […]
Western high-fat diet can cause chronic pain, according to new study
A typical Western high-fat diet can increase the risk of painful disorders common in people with conditions such as diabetes or obesity, according to a groundbreaking paper authored by a team led by The University of Texas Health Science Center at San Antonio, also referred to as UT Health San Antonio. Moreover, changes in diet […]