Living near pubs, bars and fast-food restaurants could be bad for heart health
Living close to pubs, bars and fast-food restaurats may lead to a higher risk of heart failure, according to new research published today in Circulation: Heart Failure, an American Heart Association journal. These kinds of ready-to-eat food environments typically provide unhealthy foods and drinks, and have been linked to cardiovascular diseases, said study senior author […]
Suicide Risk 8-Fold Higher After Common Reproductive Disorder Diagnosis
Suicidality was substantially higher among women diagnosed with polycystic ovary syndrome (PCOS), according to a Taiwanese population-based cohort study. PCOS-diagnosed patients had an 8.47-fold (95% CI 7.54-9.51) higher risk of attempted suicide compared with women without PCOS, Mu-Hong Chen, MD, PhD, of Taipei Veterans General Hospital in Taiwan, and colleagues found. Incidence of suicide attempts […]
More Evidence Linking ADT for Prostate Cancer to Adverse Neurocognitive Effects
Men treated with androgen deprivation therapy (ADT) for prostate cancer had a significantly higher risk of dementia and other neurocognitive disorders, according to a meta-analysis of more than 2.5 million patients. The magnitude of excess risk ranged from 20% for dementia to 66% for depression. The risk of Alzheimer’s disease, vascular dementia, and Parkinson’s disease […]
Co-Pays Hurt PrEP Use, Study Suggests
Higher out-of-pocket costs for HIV pre-exposure prophylaxis (PrEP) were projected to lead to more people discontinuing PrEP altogether in a new analysis, raising concerns about a possible rise in HIV infections. Risk-adjusted abandonment rates climbed from 5.5% among patients with no cost sharing to a projected 42.6% for patients with $500 out-of-pocket costs in a […]
Iodine Linked With Men’s Testosterone Levels
Lower iodine concentrations in the urine was independently associated with higher testosterone levels, a cross-sectional study found. Looking at nearly 3,000 U.S. men, those with lower urinary iodine concentrations had significantly higher total testosterone levels than men with either normal or high iodine levels (β -0.028, 95% CI -0.049 to -0.006, P=0.01), Arcangelo Barbonetti, PhD, […]
National Database Study Finds Higher Risk for Barrett’s Esophagus in IBD
ORLANDO – People with inflammatory bowel disease (IBD) faced higher odds of Barrett’s esophagus (BE) and BE without dysplasia, but not BE-linked malignancy, according to a cross-sectional study. Among patients diagnosed with ulcerative colitis (UC), the prevalence of BE was 0.077%, while the prevalence of BE in patients with Crohn’s disease (CD) came in at […]
Coronary Heart Disease by Age 45 Linked With Subsequent Dementia
Younger onset age of coronary heart disease was tied to higher risks of incident all-cause dementia, Alzheimer’s disease, and vascular dementia, a large prospective cohort study in Great Britain showed. Each 10-year decrease in coronary heart disease onset age was associated with a 25% increased risk of all-cause dementia, a 29% increased risk of Alzheimer’s […]
ART Births Linked to Slightly Higher Risk of Congenital Anomalies in Kids
Kids conceived using assisted reproductive technology (ART) had slightly higher risks of congenital anomalies, particularly genitourinary abnormalities, according to an Australian population-based cohort study. In the cohort of over 850,000 infants, singleton infants conceived via ART had an increased risk for major genitourinary abnormalities compared with naturally conceived singleton infants with parents with no fertility […]
Depressive Symptoms Tied to Higher Mortality Risk in U.S. Adults
Depressive symptoms were associated with a higher risk for all-cause and cardiovascular disease (CVD) mortality, according to a nationally representative prospective cohort study. Of nearly 23,700 U.S. adults, mild depressive symptoms were associated with a significantly higher risk of all-cause mortality compared with no symptoms (HR 1.35, 95% CI 1.07-1.72), as were moderate to severe […]
ADHD and Car Crashes; New Guidance on Stimulant Use Disorder Tx; KarXT Heads to FDA
Older adults with attention deficit-hyperactivity disorder (ADHD) had a significantly higher incidence of car crashes. (JAMA Network Open) Meanwhile, the estimated prevalence of ADHD in kids 4 years and up held steady — between 10.08% to 10.47% — from 2017 to 2022, according to nationally representative data. (JAMA Network Open) The FDA released new draft […]