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Metformin Protective Against Joint Replacement in Type 2 Diabetes

Among people with type 2 diabetes, use of metformin might help to stave off total joint replacement, a population-based cohort study showed. Among over 40,000 patients, daily metformin was associated with a 30% lower risk for total knee and hip replacement compared with no metformin (adjusted HR 0.70, 95% CI 0.60-0.81) over a median follow-up […]

Not So Fast for NSAID Closure of Heart Defect in Preterm Newborns

Early ibuprofen administration did not help babies born preterm with patent ductus arteriosus (PDA), as waiting for the heart defect to close on its own was associated with non-inferior, perhaps even better clinical outcomes, in a randomized trial. For infants born with moderate or larger PDAs, expectant management worked at least as well as early […]

Activity ‘snacks’ following meals may help maintain muscle mass

Interrupting prolonged sitting with periodic activity “snacks” may help maintain muscle mass and quality, according to a new study by researchers at the University of Toronto. Daniel Moore, an associate professor of muscle physiology at the Faculty of Kinesiology & Physical Eduction (KPE) who led the study, found that short bouts of activity, such as […]

Scientists chart how exercise affects the body: A new study maps the genes and cellular pathways that contribute to exercise-induced weight loss

Exercise is well-known to help people lose weight and avoid gaining it. However, identifying the cellular mechanisms that underlie this process has proven difficult because so many cells and tissues are involved. In a new study in mice that expands researchers’ understanding of how exercise and diet affect the body, MIT and Harvard Medical School […]

Electronic health record tool can help children achieve healthy weight

An electronic health record (EHR) program to help primary care doctors address child obesity is an effective tool to promote positive body mass index (BMI) trends, especially among young children with obesity, according to a new University of Missouri School of Medicine study that examined the effectiveness of the FitTastic tool over an average follow-up […]

High-fat diets trigger inflammatory immune cell generation in bone: A study suggests that high-fat diets fuel the creation of inflammatory immune cells in the bone marrow of mice.

The results may help explain how high-fat diets trigger inflammation, which can contribute to the development of insulin resistance, type 2 diabetes and other complications in individuals with obesity. An invasion of inflammatory immune cells, called monocytes, into fat tissue is a hallmark of obesity, but what leads to this harmful phenomenon is unclear. Many […]

Want Us to Find the Fountain of Youth? Give Us Endpoints, Scientists Say

WASHINGTON — Better surrogate endpoints are needed to help patients benefit from anti-aging therapies, experts told a House committee Thursday. “It would be important to develop different metrics of measuring success,” said Steve Horvath, PhD, principal investigator at Altos Labs, a San Francisco-based biotechnology company focused on cellular rejuvenation programming. “Imagine that you have a […]

U.S. Government Extends Baby Formula Waivers, Rebates for WIC Families

Latest Pregnancy News THURSDAY, Aug. 25, 2022 (HealthDay News) To help parents who use government nutrition benefits cope with an ongoing shortage of baby formula, U.S. federal officials will extend a program giving them more choice at the grocery store. Families who buy formula through the Special Supplemental Nutrition Program for Women Infants and Children […]

The Risk Factors For A Blood Clot Are More Common Than You Think

When they happen on the outside, blood clotting can be a good thing to help prevent excessive bleeding after you’ve been injured. Platelets (a type of blood cell) and proteins in your plasma (the liquid part of the blood) band together and form a clot over the injury, which eventually dissolves once the injury has […]

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