Genotype Tied to Azathioprine Discontinuation for Toxicity
Patients with inflammatory conditions who have the CC genotype were at greater risk both for discontinuing the use of azathioprine (Imuran) due to hematopoietic toxicity and for needing to switch to lower doses, a retrospective cohort study found. In a competing-risk analysis involving over 1,400 such patients starting on azathioprine, those who carried the CC […]