For Septic Shock, Another Toss-up Between Emphasizing Vasopressors Vs Fluids
SAN FRANCISCO — For sepsis-induced hypotension, a restrictive fluid strategy with earlier vasopressor use didn’t impact mortality compared with liberal fluids, the CLOVERS trial showed. The restrictive strategy had its intended effect, reducing median IV fluids administered over 24 hours by 2,134 mL in favor of more vasopressor use compared with the liberal fluids strategy […]
Adding Targeted Drug to Chemo Boosts Survival in Esophageal/GEJ Cancer
SAN FRANCISCO — Adding a Claudin (CLDN) inhibitor to chemotherapy significantly increased progression-free (PFS) and overall survival (OS) in locally advanced gastric/gastroesophageal junction (GEJ) cancer and CLDN 18.2 expression, a randomized trial showed. Median PFS increased from 8.67 months with modified FOLFOX chemotherapy to 10.61 months with the addition of investigational zolbetuximab. Median OS improved […]
More Data Needed on Monkeypox, HIV Co-Infection
San Francisco has seen some of the highest case counts of monkeypox in the U.S., and Monica Gandhi, MD, MPH, of University of California San Francisco (UCSF), said she’s seen plenty of co-infection with HIV. Gandhi cautioned that she sees a skewed population as the medical director of a large HIV clinic, “Ward 86,” at […]
San Francisco, N.Y. State Declare Monkeypox Public Health Emergencies – MedicineNet Health News
Latest Infectious Disease News MONDAY, Aug. 1, 2022 Both San Francisco and New York state declared monkeypox a public health emergency on Thursday, as they struggle to gain access to more resources to help contain the spread of the virus. About 40% of the 4,907 monkeypox cases recorded in the United States have been diagnosed […]
San Francisco, N.Y. State Declare Monkeypox Public Health Emergencies – MedicineNet Health News
Latest Infectious Disease News MONDAY, Aug. 1, 2022 Both San Francisco and New York state declared monkeypox a public health emergency on Thursday, as they struggle to gain access to more resources to help contain the spread of the virus. About 40% of the 4,907 monkeypox cases recorded in the United States have been diagnosed […]
San Francisco, New York State Declare Monkeypox A Public Health Emergency
The city of San Francisco and the state of New York declared public health emergencies on Thursday amid the growing outbreak of monkeypox. San Francisco Mayor London Breed said that the risk of monkeypox to the general population remained low but that declaring a public health emergency would allow the city to mobilize resources and […]
‘There’s Nothing to Repair’: Emergency Docs on Injuries From Assault Weapons
Last Tuesday, Christopher Colwell, MD, chief of emergency medicine at Zuckerberg San Francisco General Hospital and Trauma Center, was looking forward to a rare dinner that his entire family of five would be able to attend. He had left his shift at the emergency department and drove straight home, listening to music in the car […]
Two Drugs Better Than One for ‘Rescue’ Asthma Therapy
SAN FRANCISCO — Phase III results look very good for a two-drug combination inhaler in helping asthma patients regain symptom control when maintenance medications weren’t doing the job. In the MANDALA trial, patients using the investigational product PT027, which combines 90 μg of albuterol with 80 μg of budesonide, were significantly less likely to experience […]
Do Pediatric Electrophysiologists Have It Harder?
SAN FRANCISCO — Unlike their peers who treat adults, pediatric electrophysiologists face unique challenges of ethics and communication when working with children and their families. Clinical decision-making can be hampered by a scientific literature that is currently modest at best and evolving, and by potential disagreement between parent and adolescent about putting in an implantable […]
Menstrual Cycles Point to Link Between Sex Hormones and Long QT
SAN FRANCISCO — Cardiac repolarization dynamics seemed to cycle in sync with the menstrual cycle of some people with congenital and drug-induced long QT syndrome (LQTS), a small prospective study showed. Women with LQTS type 2 were found to have their QT interval — corrected with the Bazett formula (QTcB) and Fridericia’s method (QTcF) — […]