Peripheral IV Access for Chemo Better Than Central Lines in Testicular Cancer?
Patients with testicular cancer had fewer venous access-related complications and overall thrombotic events when first-line chemotherapy was delivered via peripheral intravenous access compared with central venous access devices (CVADs), a retrospective study suggested. Among 154 patients, those in the CVAD group compared with the peripheral IV group experienced more venous access-related complications (52.2% vs 24.2%) […]
Less Velopharyngeal Insufficiency at Age 5 With Earlier Cleft Palate Surgery
Fewer infants with isolated cleft palate who had primary surgery to close it at age 6 months had insufficient closure between their velum and pharyngeal walls later in childhood than infants who had surgery at 12 months, the TOPS clinical trial found. Among 558 infants in Europe and South America, 8.9% in the 6-month surgery […]
Higher BMI = Less Neutropenia With CDK4/6 Inhibitor for Early Breast Cancer
A higher body mass index (BMI) translated into less neutropenia and fewer discontinuations among women with early hormone receptor (HR)-positive breast cancer treated with a CDK4/6 inhibitor, a secondary analysis of the randomized trial PALLAS showed. Among patients who received palbociclib (Ibrance) in addition to endocrine therapy, increasing BMI was associated with a small but […]
Americans With Heart Disease Less Likely to Use Wearable Devices
Fewer Americans with or at risk for cardiovascular disease (CVD) used a wearable health monitoring device than the general population, according to a nationally representative sample using 2019-2020 Health Information National Trends Survey (HINTS) data. Only 18% of adults with CVD and 26% of those at risk for CVD reported using a wearable device to […]
Breathing Support Type Matters for Preventing Extubation Failure in the PICU
Postextubation use of certain modes of noninvasive respiratory support was associated with fewer incidents of extubation failure in critically ill children, a meta-analysis found. Compared with conventional oxygen therapy, both continuous positive airway pressure (CPAP; OR 0.43, 95% credible interval [CrI] 0.17-1.0) and high-flow nasal cannula (HFNC; OR 0.64, 95% CrI 0.24-1.0) appeared more effective […]
Obesity-Related Medication Use Remains Low After Bariatric Surgery
Fewer patients with obesity used lipid-lowering, cardiovascular, or antidiabetic drugs after bariatric surgery compared with matched patients who did not have surgery for morbid obesity, a population-based cohort study in Sweden and Finland found. Bariatric surgery patients had a lower probability of receiving a prescription for one of the three categories of medication in all […]
Neuromodulation of the Peroneal Nerve Safe for Overactive Bladder
Electrical transcutaneous neuromodulation (eTNM) of the peroneal nerve led to fewer side effects compared with solifenacin (Vesicare) in the treatment of overactive bladder, a randomized trial showed. Among 76 treatment-naive women randomized 2:1 to peroneal eTNM or solifenacin, 12% versus 48% reported a treatment-related adverse event (TRAE; P<0.001), reported Jan Krhut, MD, PhD, of University […]
Fewer Wyoming Resident Deaths, Births Recorded in 2022 – Wyoming Department of Health
Fewer Wyoming Resident Deaths, Births Recorded in 2022 March 14, 2023 Fewer deaths, births, marriages and divorces were recorded among Wyoming residents in 2022 compared to the previous year according to official records held by Vital Statistics Services (VSS), which is part of the Wyoming Department of Health (WDH. Among Wyoming residents, there were 5,886 […]
Combo Falters in Papillary Renal Cancer, but Some Promise in MET-Driven Subset
Treatment with an investigational MET inhibitor plus a PD-L1 inhibitor induced responses in fewer than a third of patients with metastatic papillary renal cancer, but the combination showed promise for one subgroup, findings from the phase II CALYPSO trial showed. In the single-arm study, 12 of 41 patients (29%, 95% CI 16-46) had a confirmed […]
Fewer Emergency Department Visits End With Opioid Prescriptions
Fewer emergency department (ED) visits end with a prescription for opioids, CDC survey data showed. The percentage of ED visits with an opioid prescribed at discharge fell from 12.2% in 2017-2018 to 8.1% in 2019-2020, reported Loredana Santo, MD, MPH, and Susan Schappert, MA, of the National Center for Health Statistics in Hyattsville, Maryland, in […]