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Opinion | Should Future COVID Boosters Include the Ancestral Strain?

The current COVID-19 mRNA vaccine boosters are bivalent, meaning they contain equal amounts of spike protein mRNA for the original Wuhan virus sequence and for the BA.4/5 Omicron variants that emerged in mid-2022. How well does this type of bivalent booster perform? The question is relevant because FDA’s recent Vaccines and Related Biological Products Advisory […]

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