Eosinophilic Esophagitis Risk Linked to Medications in Pregnancy, Infancy
Antibiotic and acid suppressant exposure during the perinatal period was linked to the development of eosinophilic esophagitis (EoE) later in life, a Danish cohort study found. Infants with any antibiotic use had a 40% greater risk of developing EoE later in childhood compared to matched controls without such exposure (adjusted OR 1.4, 95% CI 1.1-1.7), […]
Benralizumab Allows Inhaled Corticosteroid Taper for Asthma Patients
MILAN — Benralizumab (Fasenra) allowed patients with severe eosinophilic asthma to reduce inhaled corticosteroid (ISC) use without compromising control, the SHAMAL phase IV randomized trial found. After 32 weeks, 92% of patients on the monoclonal antibody with planned tapering from high-dose ICS plus formoterol were able to reduce their use, reported David J. Jackson, MD, […]
Forgoing one food treats eosinophilic esophagitis as well as excluding six, study finds: Results of first multi-site randomized trial comparing the two diets
Eliminating animal milk alone from the diet of adults with eosinophilic esophagitis, or EoE, is as effective at treating the disease as eliminating animal milk plus five other common foods, a clinical trial funded by the National Institutes of Health has found. For people with EoE whose disease remains active after they forgo animal milk, […]
First Treatment Approved for Eosinophilic Esophagitis
Dupilumab (Dupixent) became the first drug approved to treat eosinophilic esophagitis in adults and pediatric patients ages 12 and older weighing at least 40 kg (~88 lb), the FDA announced. Eosinophilic esophagitis is a chronic, progressive disease in which the esophagus becomes inflamed due to a buildup of eosinophils, creating difficulty swallowing and eating. Dupilumab […]