Can Pre-Op Chemo Set Stage for Organ-Sparing Surgery in Early Rectal Cancer?
Three months of induction chemotherapy resulted in successful downstaging for certain patients with early-stage rectal cancer, enabling them to undergo organ-sparing therapy, according to a phase II trial. In 33 of 58 patients, induction with modified folinic acid, fluorouracil, oxaliplatin 6 (FOLFOX6) or capecitabine-oxaliplatin (CAPOX), followed by transanal excision surgery, resulted in downstaging to ypT0/1N0/X […]