Daily Thiazide No Help in Preventing Recurrent Kidney Stones
A common diuretic wasn’t much help for staving off recurrent kidney stones, the NOSTONE trial showed. Over a median follow-up of 2.9 years, symptomatic or radiologic recurrence of kidney stones occurred in 59% of patients who received hydrochlorothiazide (12.5 mg once daily) and 59% of those assigned placebo (rate ratio [RR] 1.33, 95% CI 0.92-1.93), […]
ADVOR Backs Add-On Acetazolamide for Cutting Congestion in Decompensated HF
BARCELONA — The addition of IV acetazolamide to loop diuretic therapy led to a greater incidence of successful early decongestion in patients with acute decompensated heart failure (HF), according to the ADVOR trial. The primary outcome of successful decongestion within 3 days after randomization was 42.2% with acetazolamide versus 30.5% with placebo (P<0.001), reported Wilfried […]