Immunotherapy may get a boost
T cells are usually very good at eliminating diseased cells. But they seem to fail when it comes to tumor cells. In JCI Insight, MDC teams led by Armin Rehm and Uta Höpken describe what inhibits this immune function, how they can release the brake and boost the immune response against cancer. T cells are […]
Study shows how bioactive substance inhibits important receptor: Results raise hope for new drugs against cancer and brain diseases
The A2A receptor regulates how vigorously the innate immune system attacks diseased cells. Researchers at the University of Bonn have now been able to show for the first time how an important inhibitor binds to the receptor. In the future, the results will facilitate the targeted search for molecules that give the innate immune system […]