Metformin during pregnancy affects the brain development in offspring mice, study finds
With the rise in gestational diabetes and metabolic disorders during pregnancy, metformin is also being prescribed more frequently. Although it is known that the oral antidiabetic agent can cross the placental barrier, the impacts on the brain development of the child are largely unknown. An interdisciplinary research team from the German Institute of Human Nutrition […]
Glucose Changes in Type 1 Diabetes May Affect Thinking Speed
In type 1 diabetes, glucose fluctuations were linked with cognitive processing speed, but not sustained attention, researchers reported. According to data collected every 5 minutes from continuous glucose monitors, large fluctuations in glucose were associated with slower processing speed as measured by digital symptom matching reaction time, Zoë Hawks, PhD, of McLean Hospital in Belmont, […]
Hypertension, Diabetes in Pregnancy Affects Offspring’s Heart Health in Adolescence
NATIONAL HARBOR, Md. — Moms who had hypertensive disorders of pregnancy (HDP) or gestational diabetes mellitus (GDM) were more likely to have kids with worse cardiovascular health (CVH) in adolescence, a secondary analysis of an observational cohort study found. Adjusted models showed higher risks for less-than-ideal CVH in kids ages 10 to 14 when mothers […]
How fruit bats got a sweet tooth without sour health
A high-sugar diet is bad news for humans, leading to diabetes, obesity and even cancer. Yet fruit bats survive and even thrive by eating up to twice their body weight in sugary fruit every day. Now, UC San Francisco scientists have discovered how fruit bats may have evolved to consume so much sugar, with potential […]
Even Small Diabetes Distress Changes Clinically Important
Just a quarter of a point change in Diabetes Distress Scale-17 (DDS-17) score was enough to be clinically important, according to a secondary analysis of a clinical trial. Using data from a randomized trial of Veterans with uncontrolled type 2 diabetes, a 0.25 or greater drop in DDS-17 score was determined to be a clinically […]
Direct-to-Consumer Lab Tests Raise Ethical Questions, Researchers Say
Direct-to-consumer (DTC) laboratory tests — for the thyroid, hormonal biomarkers, or diabetes and hemoglobin A1c, for example — often had unclear terms of sale and vague privacy policies, a qualitative study showed. Of 21 U.S. companies that offered DTC lab tests, less than half declared compliance with the Health Insurance Portability and Accountability Act (HIPAA), […]
Keto for Kids With Diabetes Carries Risk, AAP Warns
Keto and other low carbohydrate diets have gained popularity for type 2 diabetes in adults, but there are safety concerns for young people, the American Academy of Pediatrics (AAP) cautioned. Restricting carbohydrates in young people at risk for or with diabetes raises concerns for growth deceleration, nutritional deficiencies, poor bone health, nutritional ketosis, and disordered […]
Low-Dose Semaglutide Can Ease Insulin Need in Early T1D, Small Series Shows
When used very early on in type 1 diabetes, a GLP-1 receptor agonist may help reduce the need for insulin, a small case series suggested. Ten adults with a new type 1 diabetes diagnosis initially received a 0.125-mg dose of weekly semaglutide (Ozempic), which was adjusted up to a maximum of 0.5 mg per week […]
My Incurable Condition Is A Potential Ozempic Side Effect. Trust Me — Weight Loss Isn’t Worth This.
Boxes of the diabetes drug Ozempic rest on a pharmacy counter on April 17 in Los Angeles. Mario Tama via Getty Images In case you’ve been living under a rock and missed the hype, Ozempic is an injectable diabetes drug that’s become popular as an off-label medication for weight loss. It mimics GLP-1, a naturally […]
COVID Cleared of Increasing Risk of Type 1 Diabetes in Kids?
COVID-19 infection didn’t appear to precipitate a diagnosis of type 1 diabetes in kids, a prospective multinational cohort study suggested. Researchers tested more than 4,500 adolescents every few months for type 1 diabetes, SARS-CoV-2 infection, and vaccination antibodies from January 2020 through December 2021. However, there was no difference among the 45 kids diagnosed with […]