National News HHS, NIH announce development of universal vaccine for COVID-19 and influenza Justin Boggs
The National Institutes of Health and the Department of Health and Human Services announced the development of a “next-generation, universal vaccine platform,” intended to create a universal COVID-19 and influenza shot that won’t require updates. Currently, the flu and COVID-19 vaccines, which are administered separately, are updated every year to best combat the active strains […]
Early vocabulary size is genetically linked to ADHD, literacy, and cognition
Early language development is an important predictor of children’s later language, reading and learning skills. Moreover, language learning difficulties are related to neurodevelopmental conditions such as Attention-Deficit/Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD). Children typically start to utter their first words between 10 and 15 months of age. At around two years of age, […]
Surgical Remission of Cushing’s Disease Tied to New Autoimmune Conditions
Development of autoimmune disease was more common in patients with surgical remission of Cushing’s disease than in those with surgically treated nonfunctioning pituitary adenomas (NFPAs), according to a retrospective matched cohort study. At 3 years after surgery, 10.4% of patients with Cushing’s disease developed new-onset autoimmune disease compared with 1.6% of those with NFPAs (HR […]
Goodbye, Appendix. Hello, Crohn’s Disease?
ORLANDO – People who undergo appendectomy may have an increased risk for the development of Crohn’s disease (CD), but not ulcerative colitis (UC), according to a systematic review and meta-analysis. The meta-analysis showed a pooled OR of 1.57 (95% CI 1.01-2.43, P<0.00001) for CD in those who had gotten surgery of the mucosa-and-gut lymphoid tissue […]
Eosinophilic Esophagitis Risk Linked to Medications in Pregnancy, Infancy
Antibiotic and acid suppressant exposure during the perinatal period was linked to the development of eosinophilic esophagitis (EoE) later in life, a Danish cohort study found. Infants with any antibiotic use had a 40% greater risk of developing EoE later in childhood compared to matched controls without such exposure (adjusted OR 1.4, 95% CI 1.1-1.7), […]
A new breakthrough in obesity research may allow you to lose fat while eating all you want
This is a significant development that brings hope to the one billion individuals with obesity worldwide. Researchers led by Director C. Justin LEE from the Center for Cognition and Sociality (CCS) within the Institute for Basic Science (IBS) have discovered new insights into the regulation of fat metabolism. The focus of their study lies within […]
Sotagliflozin Gets FDA’s Blessing for Heart Failure
After a rocky development and regulatory road, the FDA has approved sotagliflozin (Inpefa) for treating heart failure in patients with or without diabetes, manufacturer Lexicon Pharmaceuticals announced on Friday. The dual SGLT1 and SGLT2 inhibitor is indicated for reducing the risk of cardiovascular death and urgent visits or hospitalization for heart failure in adults with […]
Feds Spent Even More on PrEP Combo Than Previously Thought
The federal government may have contributed far more to the development of HIV pre-exposure prophylaxis (PrEP) than previously estimated, researchers reported. While previous estimates said the federal government spent $50 million on the development of combination tenofovir/emtricitabine, or TDF/FTC (Truvada), it actually spent at least $143 million, according to a new estimate by Frazer Tessema, […]
Diminishing health benefits of living in cities for children and teens
The advantages of living in cities for children and adolescents’ healthy growth and development are shrinking across much of the world, according to a new global analysis of trends in child and adolescent height and body mass index (BMI) led by Imperial College London and published in Nature. The research, by a global consortium of […]
High-fat diets trigger inflammatory immune cell generation in bone: A study suggests that high-fat diets fuel the creation of inflammatory immune cells in the bone marrow of mice.
The results may help explain how high-fat diets trigger inflammation, which can contribute to the development of insulin resistance, type 2 diabetes and other complications in individuals with obesity. An invasion of inflammatory immune cells, called monocytes, into fat tissue is a hallmark of obesity, but what leads to this harmful phenomenon is unclear. Many […]