Several Factors Contribute to GI Bleeding Mortality Risk
Patients who developed upper gastrointestinal (GI) bleeding during a hospital stay experienced worse adverse outcomes than those admitted for upper GI bleeding alone, French researchers found in a prospective study. Currently hospitalized patients (dubbed “inpatients”) with upper GI bleeding showed a significantly higher mortality rate at 6 weeks than patients hospitalized for GI bleeding alone […]
A ‘cousin’ of Viagra reduces obesity by stimulating cells to burn fat
Researchers at Johns Hopkins Medicine have found that a drug first developed to treat Alzheimer’s disease, schizophrenia and sickle cell disease reduces obesity and fatty liver in mice and improves their heart function — without changes in food intake or daily activity. These findings, published online Oct. 7 in the Journal of Clinical Investigation, reveal […]
New machine learning method to analyze complex scientific data of proteins: Method allows faster and more accurate data analysis from NMR spectrometers
Scientists have developed a method using machine learning to better analyze data from a powerful scientific tool: nuclear magnetic resonance (NMR). One way NMR data can be used is to understand proteins and chemical reactions in the human body. NMR is closely related to magnetic resonance imaging (MRI) for medical diagnosis. NMR spectrometers allow scientists […]
Time until dementia symptoms appear can be estimated via brain scan: Alzheimer’s dementia predicted by brain amyloid levels, age
Researchers at Washington University School of Medicine in St. Louis have developed an approach to estimating when a person who is likely to develop Alzheimer’s disease, but has no cognitive symptoms, will start showing signs of Alzheimer’s dementia. The algorithm, available online in the journal Neurology, uses data from a kind of brain scan known […]
Researchers use artificial intelligence to predict which COVID-19 patients will need a ventilator to breathe
Researchers at Case Western Reserve University have developed an online tool to help medical staff quickly determine which COVID-19 patients will need help breathing with a ventilator. The tool, developed through analysis of CT scans from nearly 900 COVID-19 patients diagnosed in 2020, was able to predict ventilator need with 84% accuracy. “That could be […]
Men and women of Roman Herculaneum had different diets, new research shows
Researchers — led by the University of York’s BioArCh team — developed a new approach to analyse amino acids, the building blocks of proteins, from 17 adult skeletons found in the aftermath of the eruption of Vesuvius in 79 AD. By measuring the isotopes of carbon and nitrogen in the bone amino acids, the researchers […]
Monoclonal antibody may prevent malaria
One dose of a new monoclonal antibody discovered and developed at the National Institutes of Health safely prevented malaria for up to nine months in people who were exposed to the malaria parasite. The small, carefully monitored clinical trial is the first to demonstrate that a monoclonal antibody can prevent malaria in people. The trial […]
New framework applies machine learning to atomistic modeling: Method could lead to more accurate predictions of how new materials behave at the atomic scale
Northwestern University researchers have developed a new framework using machine learning that improves the accuracy of interatomic potentials — the guiding rules describing how atoms interact — in new materials design. The findings could lead to more accurate predictions of how new materials transfer heat, deform, and fail at the atomic scale. Designing new nanomaterials […]
Single cancer cells have different appetites for fatty acids
A new method developed by Institute for Systems Biology (ISB) and University of California, Riverside provides new insights into cancer biology by allowing researchers to show how fatty acids are absorbed by single cells. Fatty acids, along with glucose and amino acids, are a major energy source for cellular growth and proliferation, and abnormal fatty […]
‘Neuroprosthesis’ restores words to man with paralysis: Technology could lead to more natural communication for people who have suffered speech loss
Researchers at UC San Francisco have successfully developed a “speech neuroprosthesis” that has enabled a man with severe paralysis to communicate in sentences, translating signals from his brain to the vocal tract directly into words that appear as text on a screen. The achievement, which was developed in collaboration with the first participant of a […]