Depressive Symptoms Tied to Higher Mortality Risk in U.S. Adults
Depressive symptoms were associated with a higher risk for all-cause and cardiovascular disease (CVD) mortality, according to a nationally representative prospective cohort study. Of nearly 23,700 U.S. adults, mild depressive symptoms were associated with a significantly higher risk of all-cause mortality compared with no symptoms (HR 1.35, 95% CI 1.07-1.72), as were moderate to severe […]
Antidepressant Maintenance No Help for Bipolar I Depressive Episode
Continuing adjunctive antidepressant treatment for up to a year following remission of an acute depressive episode in patients with bipolar I disorder showed no significant benefit for preventing relapse, a randomized trial showed. At 52 weeks, 31% of patients treated with maintenance escitalopram (Lexapro) or bupropion XL (Wellbutrin XL) for that duration of time experienced […]
Depressive Symptoms in Moms Linked to Unhealthy Behaviors in Teens
Maternal depressive symptoms were associated with an increase in the number of unhealthy adolescent behaviors, a 15-year longitudinal study showed. While unhealthy behaviors were found to be common among adolescents in general, with two out of three engaging in at least one, higher levels of maternal depressive symptoms during a child’s middle childhood and adolescence […]
Add-On Vraylar Tied to Easing of Recurrent Depressive Symptoms
NEW ORLEANS — Adjunctive cariprazine (Vraylar) was linked with a reduction in depressive symptoms for patients with major depressive disorder (MDD), who had an inadequate response to current therapy, according to a phase III study. When added to a first-line antidepressant, 1.5 mg of once-daily cariprazine resulted in significantly greater average reductions in Montgomery-Åsberg Depression […]
Just How Many New Depression, Anxiety Cases Popped Up in 2020?
Depressive and anxiety disorders increased substantially around the world since the start of the pandemic, hitting some groups harder than others, according to a new systematic review and meta-analyses. Two proxy measures for the impact of COVID-19 — daily infection rates and reductions in human mobility — were both significantly associated with surges in major […]