HIV Activists Organize to Save Lives as Trump Guts Funding
Cedric Sturdevant woke up with “a bit of depression” but made it to church, as he does every Sunday. In a few days, he would drive from Mississippi to Washington, D.C., to join HIV advocates at an April rally against the Trump administration’s actions. It had clawed back more than $11 billion in federal public […]
Psychedelics for Psych Conditions Made Their Mark in 2023
In January, we reported on an investigational psychedelic that alleviated symptoms of depression in a mid-stage trial. In this report, we follow up on what has happened since that study was published. In the phase IIa trial, an investigational N,N-dimethyltryptamine treatment — commonly known as the hallucinogen DMT — significantly reduced depressive symptoms by 7.4 […]
FDA OKs First Pill for Postpartum Depression
The FDA approved zuranolone (Zurzuvae) as the first oral treatment for postpartum depression, the agency announced late on Friday. Until now, brexanolone (Zulresso) has been the only other treatment with an indication for postpartum depression, but that drug requires a continuous IV infusion administered by a healthcare provider. “Postpartum depression is a serious and potentially […]
A Game-Changing Pill For Postpartum Depression Was Just Approved By The FDA
Feinstein Institute A photo of zuranolone, the first pill designed to treat postpartum depression, from its phase 3 clinical trial. The Food and Drug Administration on Friday approved the first-ever pill specifically designed to treat postpartum depression. Taken once a day for two weeks, the drug, called zuranolone and marketed as Zurzuvae, can rapidly and […]
The Sneaky Ways Postpartum Depression Shows Up At Work
boonchai wedmakawand via Getty Images Postpartum depression is all too common, and at work, it can be hard to notice. Last November, when Danae Huff-Taylor returned to work six weeks after giving birth, she felt like a different person. The San Antonio, Texas-based professional felt moody when she used to be known as a cheerful […]
Injectable Ketamine Shows Promise in Treatment-Resistant Depression
Twice-weekly subcutaneous ketamine helped alleviate symptoms of treatment-resistant depression, according to the phase III KADS study. Among those who received at least one flexible treatment dose (0.5-0.9 mg/kg), ketamine was more than 12-times better at inducing remission of depression than the benzodiazepine midazolam (remission rate 19.6% vs 2.0%, OR 12.1, 95% CI 2.1-69.2, P=0.005), reported […]
Pre-Existing Depression, Anxiety Tied to Worse DLBCL Prognosis
Patients with diffuse large B-cell lymphoma (DLBCL) who also had pre-existing depression, anxiety, or both had a worse prognosis than those without these pre-existing mental health conditions, according to results from a population-based study. Among over 13,000 patients at a median follow-up of 2 years, the 5-year overall survival (OS) rate was 27% for patients […]
Ketamine Matches ‘Gold Standard’ in Major Depression Trial
SAN FRANCISCO — When it came to improving treatment-resistant major depression in outpatients without psychotic features, ketamine worked just as well as electroconvulsive therapy (ECT), the ELEKT-D randomized trial found. Following a 3-week treatment period, 55.4% of the patients in the ketamine group and 41.2% of those in the ECT group had a treatment response, […]
Hayden Panettiere Says She Thought Alcohol Would Fix Postpartum Depression
Hayden Panettiere recently opened up about her struggles with alcohol and postpartum depression after giving birth to her daughter in 2014. “I wish I knew about postpartum depression. I wish I knew to look out for it,” Panettiere said in an interview with E! News published Friday. The actor added that she didn’t know of […]
Depressive Symptoms Linked to Higher Risk of Acute Stroke
Symptoms of depression were associated with an increased risk of acute stroke, according to an international case-control study. Among more than 26,000 participants in the INTERSTROKE study, self-reported depressive symptoms were associated with significantly greater odds of acute stroke (OR 1.46, 95% CI 1.34-1.58), including ischemic stroke (OR 1.44, 95% CI 1.32-1.58) and intracerebral hemorrhage […]