Novel IDH1/2 Inhibitor Shows ‘Dramatic Effect’ in Low-Grade Glioma
CHICAGO — Oral vorasidenib monotherapy significantly improved progression-free survival (PFS), and delayed the time to next therapy, in patients with mutated, low-grade glioma, according to an interim analysis of the INDIGO trial. Among 331 patients with grade 2 isocitrate dehydrogenase (IDH)-mutant glioma, who received no prior treatment other than surgery, those randomly assigned to receive […]
My Muscles Mysteriously Began Growing So Fast I Thought They Might Kill Me
In November 2007, a communication glitch delayed scheduling a doctor’s appointment, and I almost exploded. This would be the seventh doctor I’d seen in eight months because my muscles had grown so big. They looked buff, but my muscles also tightened and weakened as they grew. My biceps had grown too muscular and weak for […]
Ready, set…GO! Scientists discover a brain circuit that triggers the execution of planned movement
Planned movement is essential to our daily lives, and it often requires delayed execution. As children, we stood crouched and ready but waited for the shout of “GO!” before sprinting from the starting line. As adults, we wait until the traffic light turns green before making a turn. In both situations, the brain has planned […]
7 Happiness Hacks You Can Do On A Commute
Commuting can be tedious, no matter the circumstances. Traffic is a nightmare, subways can be packed, trains can get delayed. Even walking or biking to your destination can come with frustrations. Since we can’t avoid commuting altogether, why not take advantage of having to get from point A to point B? Better yet, why not […]
When Is ADT Right for Biochemically Recurrent Prostate Cancer?
Men with prostate cancer and biochemical recurrence (BCR) who delayed androgen deprivation therapy (ADT) still experienced long survival outcomes, researchers reported. In a retrospective study, men with a prostate-specific antigen doubling time (PSADT) of less than 10 months saw a median metastases-free survival (MFS) of 192 months when they delayed ADT until metastasis, and a […]