Dapivirine Vaginal Ring, Oral PrEP Safe for HIV Prevention in Pregnancy
DENVER — The monthly dapivirine ring to reduce risk of HIV in women showed similar safety outcomes as oral pre-exposure prophylaxis (PrEP) when used throughout the second and third trimesters of pregnancy, according to a phase IIIb open-label trial in sub-Saharan Africa. Premature births occurred in 4% of those with the ring, compared with 6% […]
Vaginal Ring as Safe as Oral PrEP in Late Pregnancy
The long-acting dapivirine vaginal ring, which reduces HIV risk in young women, had a comparable safety profile in late pregnancy to an oral daily pre-exposure prophylaxis (PrEP) regimen, according to an interim analysis of a small open-label trial in sub-Saharan Africa. Adverse pregnancy outcomes were rare, with one stillbirth and one neonatal death in the […]