Need 10,000 Daily Steps to Prevent Obesity? It May Depend on Genetics
The daily step count needed to reduce the risk of obesity may be largely dependent on genetics, a retrospective cohort study indicated. Among U.S. adults without obesity in the All of Us Research Program, incidence of obesity over a median follow-up of 5.4 years was 13% for those in the lowest quartile of BMI polygenic […]
Monthly ART Injections Top Pills for HIV Patients With Adherence Problems
Long-acting cabotegravir/rilpivirine (Cabenuva; CAB/RPV-LA) appeared superior to daily oral antiretroviral therapy (ART) in maintaining viral load suppression for people living with HIV who have trouble adhering to oral ART, according to an interim analysis of a phase III trial. At 52 weeks, numerically fewer patients assigned to monthly injections of CAB/RPV-LA experienced regimen failure — […]
Investigational Agent Shows Benefit in Myasthenia Gravis
The investigational monoclonal antibody batoclimab led to significant improvement in activities of daily living in people with generalized myasthenia gravis (gMG), a multicenter phase III trial found. The rate of sustained improvement on Myasthenia Gravis Activities of Daily Living (MG-ADL) scores for antibody-positive patients in the first treatment cycle was 58.2% in the batoclimab group […]
Increasing BMI in Kids Tied to 100% Fruit Juice Consumption
Daily consumption of 100% fruit juice was associated with a small increase in body mass index (BMI) in children, while an association between consumption and weight gain among adults appeared mixed, a systematic review and meta-analysis found. In prospective cohort studies involving kids, each 8-oz serving of 100% fruit juice was associated with a 0.03 […]
5 Habits That Can Drastically Improve Your Brain Health
Cavan Images via Getty Images There are a few daily habits that can improve your cognitive function and lower your risk for Alzheimer’s. As crucial as our brains are to our ability to function, they don’t get nearly the attention that certain muscle groups (or even wrinkles) do. Unless we’re dealing with a serious condition, […]
Daily Low-Dose Aspirin Upped Incidence of Anemia in Older Adults
Daily low-dose aspirin increased incident anemia among otherwise healthy older adults, a secondary analysis of the randomized ASPREE trial showed. Over a median of 4.7 years, the incidence of anemia was 51.2 events per 1,000 person-years in the aspirin group compared with 42.9 events per 1,000 person-years in the placebo group (HR 1.20, 95% CI […]
Multivitamin improves memory in older adults, study finds
Taking a daily multivitamin supplement can slow age-related memory decline, finds a large study led by researchers at Columbia University and Brigham and Women’s Hospital/Harvard. “Cognitive aging is a top health concern for older adults, and this study suggests that there may be a simple, inexpensive way to help older adults slow down memory decline,” […]
Can High-Dose Vitamin D Prevent Diabetes?
Daily higher-dose vitamin D supplementation may help stave off diabetes in an at-risk population, researchers reported. In a meta-analysis of three randomized clinical trials, vitamin D reduced the risk for type 2 diabetes by 15% in people with prediabetes (adjusted HR 0.85, 95% CI 0.75-0.96) in a model adjusted for age, gender, body mass index […]
Instead Of A Hot Or Cold Shower, Consider A Contrast Shower
For many, the daily shower is a sacred ritual, a time to disconnect and relax with pampering products under a steady water flow. I like to use eucalyptus mist and listen to calming music to create a spa environment. Sometimes I even do a cold rinse at the end to mimic that spa cold plunge […]
Long-Acting HIV Drug Promising for Treatment-Naive Patients
Lenacapavir (Sunlenca) given every 26 weeks along with daily antiretroviral therapy (ART) suppressed HIV on par with conventional regimens in the first-line setting in the phase II CALIBRATE trial. Viral suppression to fewer than 50 copies/mL at week 54 was 85-90% across all three groups given the drug whether orally or subcutaneously every 26 weeks […]