Surgical Remission of Cushing’s Disease Tied to New Autoimmune Conditions
Development of autoimmune disease was more common in patients with surgical remission of Cushing’s disease than in those with surgically treated nonfunctioning pituitary adenomas (NFPAs), according to a retrospective matched cohort study. At 3 years after surgery, 10.4% of patients with Cushing’s disease developed new-onset autoimmune disease compared with 1.6% of those with NFPAs (HR […]
Osilodrostat Resolves Most Physical Signs of Cushing’s Disease
SAN DIEGO — Osilodrostat (Isturisa) improved many physical features associated with Cushing’s disease, according to additional findings from the phase III LINC-3 study. Among 137 adults with Cushing’s disease, a 39.5% improvement in central obesity scores was observed from baseline to week 72 with osilodrostat, reported Alberto Pedroncelli, MD, PhD, of Recordati AG in Basel, […]