Clinical Challenges: Managing Pediatric Crohn’s Disease
Pediatric Crohn’s disease (CD) is on the rise, with an estimated 40,000 U.S. children affected by this potentially growth-stunting condition. This increase is not an artifact of better detection. “Rather, it appears that Western diets, antibiotic exposure early in life, and dietary emulsifiers may contribute to disease pathogenesis,” said Jeffrey Hyams, MD, of Connecticut Children’s […]
Goodbye, Appendix. Hello, Crohn’s Disease?
ORLANDO – People who undergo appendectomy may have an increased risk for the development of Crohn’s disease (CD), but not ulcerative colitis (UC), according to a systematic review and meta-analysis. The meta-analysis showed a pooled OR of 1.57 (95% CI 1.01-2.43, P<0.00001) for CD in those who had gotten surgery of the mucosa-and-gut lymphoid tissue […]
Contrary to Guidelines, 5-ASA Often Prescribed in Pediatric Crohn’s Disease
DENVER — Even though guidelines discourage the use of 5-aminosalicylate (5-ASA) in pediatric Crohn’s disease, a substantial percentage of children are still being treated with the anti-inflammatory agent, which may cause problems down the road, a researcher reported here. Of nearly 700 children diagnosed with Crohn’s disease and treated at specialized centers, 28% were initially […]
A Child’s Pet Dog May Shield Them From Crohn’s Disease
Latest Digestion News TUESDAY, May 24, 2022 (HealthDay News) Add a lower risk of Crohn’s disease to the many benefits of having a dog during childhood, a new study suggests. Sorry, cat lovers, researchers didn’t find a similar benefit for you. “We did not see the same results with cats, though we are still trying […]
For pediatric patients with Crohn’s disease, factors associated with statural growth differ by sex
Growth impairment, a common complication of Crohn’s disease in children, occurs more often in males than females, but the reasons are unclear. Now, a physician-scientist from Weill Cornell Medicine and NewYork-Presbyterian and colleagues at eight other centers have found that factors associated with statural growth differ by sex. Their recent publication, identified as the “Editor’s […]