Gabapentinoids in COPD Patients May Raise Risk for Severe Exacerbations
Gabapentinoid use in patients with chronic obstructive pulmonary disease (COPD) was associated with a higher risk for severe exacerbations, a population-based cohort study from Canada indicated. Among more than 27,000 COPD patients, those who started therapy with the anticonvulsant for either epilepsy, neuropathic pain, or some other form of chronic pain had a 39% greater […]
Acetazolamide May Help COPD Patients Reach New Heights
Acetazolamide may prevent some patients with chronic obstructive pulmonary disease (COPD) from suffering altitude-related adverse health effects (ARAHE) when traveling, a randomized controlled trial showed. In patients with moderate to severe COPD traveling to and staying for 2 days at 3,100 m, ARAHE occurred in 50% of those taking acetazolamide compared with 74% of those […]
Targeting Bacteria in COPD Shows Promise
One study of an immunotherapy for reducing chronic obstructive pulmonary disease (COPD) exacerbations missed its primary endpoint and failed to show a statistically significant benefit even in the subgroup that showed the greatest response. Another study, involving a similar product, showed results so dramatic that an independent expert suspected they were “too good to be […]