FDA Approves Antibiotic Combination for Complicated UTIs
The FDA approved the combination of cefepime and enmetazobactam (Exblifep) for the treatment of adult patients with complicated urinary tract infections, including pyelonephritis. The agency’s decision was based on data from the phase III ALLIUM trial in which the β-lactam/β-lactamase inhibitor combination demonstrated superiority over piperacillin/tazobactam. Clinical efficacy was shown for Pseudomonas aeruginosa and among […]