Colchicine Stumbles for Protecting the Heart From Thoracic Surgery
AMSTERDAM — Anti-inflammatory colchicine (Lodoco) given perioperatively around major non-cardiac thoracic surgery did not cut atrial fibrillation (Afib) or myocardial injury complications, the COP-AF trial showed, although with some positive post hoc endpoints. Clinically important Afib occurred in 6.4% of colchicine-treated patients and 7.5% of placebo recipients (HR 0.85, 95% CI 0.65-1.10, P=0.22), David Conen, […]