Modeling a devastating childhood disease on a chip: Environmental Enteric Dysfunction (EED) Chip reveals effects of nutrition and genetics on disease in children
Millions of children in low- and middle-income nations suffer from environmental enteric dysfunction (EED), a chronic inflammatory disease of the intestine that is the second leading cause of death in children under five years old. EED is a devastating condition that is associated with malnutrition, stunted growth, and poor cognitive development, permanently impacting patients’ quality […]
Bump in Non-Opioid Pain Prescriptions Following CDC’s 2016 Guidelines
Non-opioid pain medication prescribing increased after the CDC published guidelines on opioids for chronic pain in 2016, according to a cohort study using insurance claims data. Among over 15 million individuals, logistic regression models showed that the odds of non-opioid pain prescriptions were higher following the release of the “Guideline for Prescribing Opioids for Chronic […]
Evidence of CTE Rare in Military Personnel
Evidence of chronic traumatic encephalopathy (CTE) was found in a small percentage of brains of deceased military personnel, researchers reported. Among 225 consecutive brains from a brain bank of deceased service members, investigators found signs of CTE in 4.4% (n=10), said Daniel Perl, MD, of the Uniformed Services University in Bethesda, Maryland, and colleagues. Half […]
Cannabis products demonstrate short-term reduction in chronic pain, little else, review finds: In a systematic review of scientific literature, researchers find thin evidence that cannabis has clinical benefits
Evidence behind the effectiveness of cannabis-related products to treat chronic pain is surprisingly thin, according to a new systematic evidence review by researchers at Oregon Health & Science University. The federally funded review, which will be updated on an ongoing basis, was published today in the Annals of Internal Medicine. Researchers did find evidence to […]
Chronic Total Occlusion PCI Is Getting Safer — At Least Until the Pandemic
ATLANTA — Percutaneous coronary intervention for chronic total occlusion (CTO PCI) has improved in success rates, but the pandemic might have impacted complication rates, a registry study showed. Technical and procedural success rates steadily improved over time from 2016 to 2021, rising from 81.6% to 88.1% and 80.0% to 87.0%, respectively (both P<0.0001). And the […]
What Works Best for Ruptured Achilles Tendons?
Latest Chronic Pain News By Amy Norton HealthDay Reporter THURSDAY, April 14, 2022 (HealthDay News) A ruptured Achilles tendon can reduce a weekend warrior to a limping one. And there’s no single right way to treat it. People who’ve suffered this common injury may fare just as well with physical therapy as with surgery, a […]
Even With CKD, Patiromer Helped Heart Failure Patients Keep Hyperkalemia at Bay
Regardless of chronic kidney disease (CKD) stage, the potassium-binding agent patiromer (Veltassa) improved serum potassium levels in patients with heart failure, according to a prespecified CKD subanalysis from the DIAMOND trial. In a subgroup of patients with heart failure with reduced ejection fraction plus CKD, and hyperkalemia due to renin-angiotensin-aldosterone system inhibitors (RAASi), patiromer significantly […]
Are Addiction and Substance Abuse Disorder the Same?
Addiction is a chronic disorder where the affected person seeks out drugs despite harmful consequences. Addiction is also associated with changes to your brain. It is a severe form of substance use disorder. The National Institute on Drug Abuse (NIDA) defines addiction as a chronic disorder where the affected person seeks out drugs despite harmful […]
Medical Marijuana Rx Ups Odds for Overuse, With No Benefit to Health: Study
Latest Chronic Pain News By Steven Reinberg HealthDay Reporter FRIDAY, March 18, 2022 (HealthDay News) Using medical marijuana to treat pain, anxiety or depression may quickly lead to dependence, without relieving symptoms, a new study suggests. Those most at risk for misusing medical marijuana are patients using it to treat anxiety and depression, the researchers […]
When Is It Time for a Knee Replacement?
Latest Chronic Pain News SATURDAY, March 19, 2022 (HealthDay News) Knee replacement surgery is one of the most common procedures in the United States, with more than 790,000 performed each year. Deciding the time for knee replacement needs to be determined by you and your doctor, but certain factors make it more likely, according to […]