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Kids Exposed to Smoke In Utero Had Better Lung Function If Moms Popped Vitamin C

Mothers who smoked cigarettes during pregnancy, but also took vitamin C supplements, had children with improved airway function and lower risk of wheeze later on, according to a follow-up study of a randomized trial. At 5 years, kids born to mothers who smoked and took daily vitamin C during pregnancy had 17.2% higher average forced […]

Early Promise With Fluoxetine for Refractory Nocturnal Enuresis in Children

Children with refractory primary monosymptomatic nocturnal enuresis (PMNE) obtained significant short-term symptom relief with the selective serotonin reuptake inhibitor (SSRI) fluoxetine, a small placebo-controlled trial showed. Two-thirds of patients in the fluoxetine arm had more than a 50% reduction in wet nights by 4 weeks, as compared with 16.7% of the placebo group. By 12 […]

How One Children’s Hospital Is Confronting a ‘Sick Season’ Surge

Children have been presenting in large numbers and with more severe viral illnesses than typically seen, physicians at Children’s Hospital of Philadelphia (CHOP) said. The CHOP healthcare system, which includes two hospitals and more than 600 beds, is still grappling with a high volume of pediatric patients with viral infections, including respiratory syncytial virus (RSV), […]

Children in Clinical Trials: FDA’s Proposed Rules of Engagement

FDA issued draft guidance on ethical considerations and special safeguards for having children participate in clinical trials. The new statement addresses how to protect children in clinical investigations for drugs, biological products, and medical devices. Some of the fundamental concepts that the new guidance included for consideration by industry, sponsors, and institutional review boards (IRBs) […]

CAR-T Therapy Effective in Youngest Kids With ALL

The use of tisagenlecleucel (Kymriah) in children younger than 3 years of age with relapsed or refractory B-cell acute lymphoblastic leukemia (ALL) was as effective, and safe, in a retrospective cohort study as it was previously seen to be for older children in the ELIANA trial. In an analysis of 38 patients – most of […]

Pregnant women with obesity and diabetes may be more likely to have a child with ADHD: Study only finds this association in women with excessive weight gain during pregnancy

Children of women with gestational diabetes and obesity may be twice as likely to develop attention-deficit/hyperactivity disorder (ADHD) compared to those whose mothers did not have obesity, according to new research published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism. The estimated number of children aged 3-17 years ever diagnosed with ADHD is […]

Mothers in WIC Program Have Better Birth Outcomes, Lower Infant Mortality

Mothers enrolled in the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) may experience improved birth outcomes and a lower risk of infant mortality, according to a systematic review. Women who participated in WIC had reduced risks of preterm birth (10% to 15%) and low birthweight (11% to 24%), reported S. Michelle Ogunwole, […]

Food texture key to eating habits in children with Down syndrome

Children with Down syndrome prefer food with a crispy, oily mouthfeel and don’t like brittle or gooey foods. But those preferences can lead to a less nutritious diet, according to Washington State University research published in the Journal of Texture Studies. “Children with Down syndrome really enjoy foods like Pirate’s Booty and puffed corn,” said […]

Opinion | Virtual Reality Can Help Get Our Patients Vaccinated

Whether it is the newly approved COVID-19 vaccines or school-required immunizations, many children receive their mandatory shots over summer vacation. Estimates show that as many as two-thirds of children and one-fourth of adults have strong fears around needles. Despite the past few years’ extensive coverage of the political and cultural objections to vaccinations, procedural anxiety […]

Remote Behavioral Therapy Works for Kids With Tic Disorder

For reducing tic severity in children with Tourette syndrome, an online behavioral therapy worked as well as internet-based education alone and had better participant response, a small randomized trial found. The intervention — 10 weeks of a therapist-supported, internet-delivered exposure and response prevention (ERP) program — was associated with a mean reduction of 6.08 points […]

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