Study Confirms Better Survival for HPV-Positive Cervical Cancer
Cervical cancer associated with detectable human papillomavirus (HPV+) RNA or DNA had significantly better outcomes, including survival, a large meta-analysis of published studies showed. Patients who tested positive for HPV had a 62% improvement in disease-free survival (DFS), 44% improvement in cancer-specific survival (CSS), and 41% improvement in overall survival (OS), as compared with patients […]
Sexual Health Not Part of Discussion for Women Undergoing Brachytherapy
SAN ANTONIO — Despite the fact that both men and women who receive brachytherapy for prostate or cervical cancer may experience some degree of sexual dysfunction, physicians are much less likely to engage in discussions about sexual health with women than with men, according to research presented here. A single-center study found a striking difference […]
Durvalumab-CRT Pairing Disappoints in Locally Advanced Cervical Cancer
NEW YORK — An immunotherapy-chemoradiotherapy (CRT) combination did not boost progression-free survival (PFS) in untreated, locally advanced cervical cancer, according to CALLA trial findings. Newly diagnosed patients who received durvalumab (Imfinzi) plus standard CRT did not experience a statistically significant PFS improvement versus patients who received placebo plus CRT (hazard ratio 0.84, 95% CI 0.65-1.08, […]
HPV Vaccination Close to Surgery May Reduce Recurrent Cervical Lesions
Vaccination for human papillomavirus (HPV) near the time of surgery for precancerous cervical lesions significantly reduced the rate of lesion recurrence, a meta-analysis showed. Overall, vaccination reduced the risk of recurrent cervical intraepithelial neoplasia grade 2+ (CIN2+) by 57% as compared with surgery alone. An even larger risk reduction (74%) occurred when the analysis was […]
Is Cervical Lymphadenopathy Serious? Symptoms, Treatment, Causes
Cervical lymphadenopathy is not considered a serious condition in itself; however, it may point to certain infections and some types of cancer. Cervical lymphadenopathy refers to the condition in which swelling occurs in the lymph nodes present in the neck. It is not considered a serious condition in itself, but in a few cases, it […]
HPV Immunization Program Slashed New Cervical Cancer Cases
The introduction of a human papillomavirus (HPV) immunization program in England substantially reduced cases of cervical cancer and incidence of grade 3 cervical intraepithelial neoplasia (CIN3) in young women, particularly those who received the vaccine at the age of 12 or 13, researchers found. In their register-based population study, estimated relative reductions in cervical cancer […]