Blended antioxidant supplement improves cognition and memory in aged mice
Cell damage from oxidative stress is a major underlying cause of age-related cognitive and muscle strength decline. Antioxidants can reduce oxidative stress and prevent age-related health decline. A new study has found that mice administered with a blended antioxidant supplement show significant improvements in spatial cognition, short-term memory, and mitigated age-related muscle decline. The study […]
Standard Drug Tx as Good as Stem Cell Transplant for Scleroderma?
Patients who underwent autologous stem cell transplantation (ASCT) for diffuse cutaneous systemic sclerosis (dcSSc), also known as scleroderma, did no better than others receiving conventional treatment, researchers found. In an analysis of systemic sclerosis patients enrolled in an Australian cohort study, those who would have been eligible for ASCT in either of two clinical trials […]
Vismodegib-RT Regimen Achieves High Rate of Disease Control in Head and Neck BCC
More than 90% of patients with locally advanced basal cell carcinoma (BCC) of the head and neck achieved locoregional control (LRC) with vismodegib (Erivedge) and radiation therapy (RT), a small clinical trial showed. LRC at 1 year was 91% after vismodegib induction therapy followed by concurrent vismodegib and RT. The overall response rate was 63% […]
Oldest Patient ‘Cured’ of HIV Still in Remission 5 Years After Transplant for AML
A 68-year-old man with HIV-1 who underwent hematopoietic cell transplant (HCT) for acute myelogenous leukemia 5 years ago has been free of HIV infection for 35 months after stopping antiretroviral treatment (ART), according to a case report. The patient received an HCT from a donor with the rare delta-32 mutation, which causes a CCR5 deletion […]
Companies Market Stem Cell Treatments to Long COVID Patients
Clinics that sell stem cell and exosome treatments have turned their attention to long COVID patients, researchers found. Among 38 businesses selling such treatments for COVID-19, the majority (36) marketed those therapies for long COVID, stated Leigh Turner, PhD, of the University of California Irvine, and colleagues in Stem Cell Reports. “We didn’t think the […]
Mice eating less of specific amino acid — overrepresented in diet of obese people — live longer, healthier
A new study in mice, published recently in the journal Cell Metabolism, shows that cutting down the amount of a single amino acid called isoleucine can, among other benefits, extend their lifespan, make them leaner and less frail as they age and reduce cancer and prostate problems, all while the mice ate more calories. There’s […]
Fresh Blood Not Always the Best Blood?
Longer storage of red blood cell (RBC) units was associated with longer transplant survival in kidney transplant patients receiving early transfusions, a retrospective study in France found. Among 3,483 kidney recipients who received RBC transfusions within 14 days posttransplant, each additional day of RBC storage was associated with a non-significant 1% reduction in the risk […]
Opinion | Dignity for the Deceased: The Need for Federal Regulations
Champney is a professor of cell biology, and a body donor program coordinator. A faculty colleague at another institution contacted me to let me know that his mother had donated her body to our body donation program. I replied that we would take care of her and treat her with the respect and dignity she […]
Be Wary of Amniotic Fluid Eye Drops, FDA Says
In its ongoing battle against companies selling unapproved stem cell products, the FDA issued a safety communication earlier this month about amniotic fluid eye drops being improperly marketed for dry eye disease. The communication links to earlier letters to two manufacturers — makers of Regener-Eyes and StimulEyes — warning that the products would need an […]
Simple addition to corn bran could boost grain’s nutritional value 15-35%
What if, by adding a couple of cell layers inside a corn kernel, the grain could become significantly richer in essential nutrients like iron, zinc, and protein? Such an improvement could benefit people who rely on corn for a large portion of their diet, as in many parts of the global south. In a new […]