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After Lariat LAA Ligater Disappoints in aMAZE, is a Path Ahead Still Possible?

Adjunctive left atrial appendage (LAA) ligation failed to increase the efficacy of catheter pulmonary vein isolation (PVI) in the aMAZE trial, though it appeared safe enough for further clinical investigation. In a population of people with nonparoxysmal atrial fibrillation (Afib), LAA ligation plus PVI was associated with no better primary effectiveness by 12 months — […]

Afib Ablation Exceeds Expectations in Sickest Heart Failure Patients

AMSTERDAM — Catheter ablation conferred large clinical benefits to people with end-stage heart failure and symptomatic atrial fibrillation (Afib) in the small CASTLE HTx randomized trial that was terminated prematurely for efficacy. The trial, originally planned for 2 years, was brought to a halt upon the discovery that these patients undergoing catheter ablation had fewer […]

Intraoperative Catheter Disappoints for Urinary Retention After Hernia Repair

The use of an intraoperative catheter did not protect against the development of postoperative urinary retention (PUR) for patients who underwent laparoscopic inguinal hernia repair surgery, a randomized trial found. Among over 450 such patients, no significant difference was observed in the rate of PUR for those who received an intraoperative catheter placement versus those […]

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