I’m A Colorectal Cancer Doctor. Here Are 5 Things I’d Never Do.
SDI Productions via Getty Images An oncologist for gastrointestinal cancers told HuffPost which behaviors can lead to colon cancer risk, and the signs you should look for. Colorectal cancer is the third-most common type of cancer around the world. In the earlier stages, it can be tough to catch. The symptoms, like diarrhea, abdominal pain […]
Another COVID Toll: Over 134,000 Undiagnosed Cancers During Height of Pandemic
More than 134,000 cancers might have gone undiagnosed during the first 10 months of the COVID-19 pandemic, according to a study of national trends in cancer incidence. Annual cancer incidence fell almost 30% short of the expected rate from March through December 2020. The difference represented potentially 134,395 undiagnosed cancers during that period. Diagnosis of […]
Deaths From PSA-Detected Prostate Cancer Low at 15 Years, No Matter the Treatment
For prostate cancers detected by screening, cancer-specific mortality was low at 15-year follow-up regardless of whether patients underwent active monitoring, prostatectomy, or radiotherapy, results from the phase III randomized ProtecT study showed. Among over 1,600 men from the U.K. with prostate cancers detected by a prostate-specific antigen (PSA) test, death from their malignancy occurred in […]
High PSMA Predictive of Good Response to Radioisotope Therapy in Prostate Cancer
Uptake of a transmembrane protein, which is expressed by virtually all prostate cancers, on imaging could be a viable predictive biomarker of patient response to isotope-based therapy, according to data from the phase II TheraP trial. High baseline prostate-specific membrane antigen (PSMA) uptake on PET was predictive of a favorable response to treatment with lutetium-177 […]
Solid tumors use a type of T cell as a shield against immune attack
An unexpected trick in cancer’s playbook may fool an important component of our immune systems into knocking down our natural defenses against solid tumors. Scientists at Fred Hutchinson Cancer Center say this newfound vulnerability involves a misuse of a type of T cell, part of a large family of blood cells that are essential to […]
FDA Approves First Drug for Von Hippel-Lindau-Associated Tumors
The FDA has approved the first therapy for cancers associated with von Hippel-Lindau (VHL) disease. Belzutifan (Welireg), distributed by Merck, targets hypoxia-inducible factor 2α, which drives growth of malignant and benign tumors in VHL. In the absence of approved systemic therapies, most patients with VHL undergo multiple surgeries in their lifetime to remove renal cell […]
‘Frameshifting’ therapy for mast cell cancers reduces size, spread
A potential new treatment for mast cell cancers reduces the number of mast cells by “mutating” the messenger RNA (mRNA) before it can deliver instructions for manufacturing the gene responsible for cell proliferation. The method, known as frameshifting, changes the pre-mRNA so that the mature mRNA is degraded and any protein produced from its instructions […]