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Immuno-Oncology Combo Active in Recurrent EGFR/ALK Positive NSCLC

Patients with recurrent EGFR/ALK-positive non-small cell lung cancer (NSCLC) obtained durable remissions with the combination of pembrolizumab (Keytruda) and chemotherapy, a small prospective study showed. The immuno-oncology (IO) combination led to a median progression-free survival (PFS) of 8.3 months in EGFR-mutant NSCLC and overall survival (OS) of 22.2 months. The combination had limited activity in […]

Sen. Amy Klobuchar Treated for Breast Cancer

Latest Cancer News THURSDAY, Sept. 9, 2021 (HealthDay News) U.S. Sen. Amy Klobuchar revealed Thursday that she’s been treated for early-stage breast cancer, including surgery to remove a lump and radiation therapy. The 61-year-old Minnesota Democrat said in a statement posted on social media that Mayo Clinic doctors found worrying signs during a […]

Stem-like T cells could aid immunotherapy in cancer treatment

In a new study by Yale Cancer Center, researchers show stem-like T cells within certain lymph nodes could be natural cancer fighters. Targeting these T cells, which are a type of white blood cells, with immunotherapy drugs could increase the number of cancer patients that respond to treatment. The findings were reported online today in […]

ADT Options for Prostate Cancer Come Out Even for Heart Safety

Androgen deprivation therapy (ADT) options for prostate cancer seemed to have a similar impact on the risk of cardiovascular events among people with documented heart disease, according to results from the PRONOUNCE trial, although the study was terminated early due to slow accrual. In 545 men, there was no statistically significant difference in the rate […]

Improved Survival With Surgery in Metastatic Breast Cancer

Selected patients with metastatic breast cancer at diagnosis had significantly better survival with surgery in addition to systemic therapy, an analysis of almost 13,000 patients showed. Overall, the survival hazard improved by 27%-36% in women with known receptor status (estrogen, progesterone, and HER2) treated with systemic therapy plus surgery with or without radiation therapy. Women […]

Surveillance for Prostate Cancer Is on the Rise — Do Men Stick It Out?

While the uptake of active surveillance (AS) for low-risk prostate cancer has increased over time, about half of patients eventually discontinue this strategy, according to an observational Canadian population-based study. The use of AS increased from 38% in 2008 to 69% in 2014; however, over this study period, 50.8% of patients discontinued AS and proceeded […]

Mom’s Obesity During Pregnancy Linked to Colon Cancer in Offspring

Overweight and obesity in mothers during pregnancy increased the risk for colorectal cancer (CRC) in their children later on in life, according to a population-based study. Compared with underweight/healthy weight during pregnancy, both obesity and overweight were associated with increased risk of CRC in offspring (adjusted HR 2.51, 95% CI 1.05-6.02 and adjusted HR 2.12, […]

This 2-Minute Strategy Can Get Your Patients Vaccinated Against COVID

I am a gastroenterologist. I do colonoscopies to remove polyps to prevent colon cancer. I never thought I would be speaking to patients about vaccinations. That has changed with COVID-19. Everything has changed with COVID-19. There is so much misinformation and everyone has seen this term: vaccine hesitancy. The vaccine-hesitant are people who are not […]

Study Confirms, Clarifies Excess Mortality in Testicular Cancer Survivors

Platinum-based chemotherapy (PBCT) and radiation therapy (RT) for testicular cancer significantly increased the risk of premature death from other causes, especially secondary cancers, a large Norwegian study showed. Overall, the 5,700 men included in the analysis had a 23% excess mortality from causes other than testicular cancer after treatment with PBCT or RT, as compared […]

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