Metastasis-Directed Therapy May Delay ADT in Advanced Prostate Cancer
Metastasis-directed therapy (MDT) in selected patients with recurrent oligometastatic prostate cancer led to PSA responses in a majority of patients and delayed initiation of hormonal therapy by 18 months, a retrospective study showed. Overall, 77 of 124 patients had PSA declines of more than 50% with surgery or stereotactic body radiation therapy (SBRT). In particular, […]
Lung Cancer Survival High for Patients With Early, Screen-Detected Tumors
CHICAGO — The diagnosis of early-stage lung cancer with low-dose CT (LDCT) screening led to high rates of lung cancer-specific survival two decades later, according to I-ELCAP data. The 20-year lung cancer-specific survival rate was 80% for the 1,285 I-ELCAP participants diagnosed with early-stage disease, reported Claudia Henschke, MD, PhD, of Mount Sinai Icahn School […]
Tackling the Global Burden of Liver Cancer
MedPage Today brought together three leaders in the field of liver cancer to discuss the latest research and clinical advances. In this last of four exclusive episodes, moderator Ghassan K. Abou-Alfa, MD, of Memorial Sloan Kettering Cancer Center in New York City, is joined by Amit Singal, MD, of UT Southwestern Medical Center in Dallas, […]
RT After Breast-Conserving Surgery Shows No Survival Advantage Decades Later
Radiotherapy after breast-conserving surgery for early breast cancer substantially reduced the risk of disease recurrence, yet the benefit did not translate to an improvement in overall survival (OS) at 30 years, a long-term analysis of the Scottish breast conservation trial showed. Compared with no radiotherapy, adjuvant locoregional radiotherapy reduced the risk of ipsilateral breast tumor […]
Dietary change starves cancer cells, overcoming treatment resistance: Laboratory research finds a low-protein diet can enhance standard treatment for colon cancer
A dietary change could be a key to enhancing colon cancer treatment, a new study from the University of Michigan Rogel Cancer Center finds. Cancer cells need nutrients to survive and grow. One of the most important nutrient sensing molecules in a cell is called mTORC1. Often called a master regulator of cell growth, it […]
Primary Care Visits Prior to Cancer Diagnosis Tied to Lower Mortality
Regularly visiting a primary care physician (PCP) before cancer diagnosis was associated with better disease outcomes among a cohort of patients from the Veterans Affairs health system. Compared with no prior visits, annual PCP use among over 200,000 veterans with 12 different tumor types was linked with lower odds of being diagnosed with metastatic disease […]
A Fork in the Road on My ‘Cancer Journey’
For the past 12 years, I have been focused on my diagnosis of low-risk prostate cancer, and in 2016, I began sharing my experience and covering the latest developments in the field in my “A Patient’s Journey” blog for MedPage Today. But in recent months, a few events reminded me that prostate cancer isn’t my […]
Could a Plant-Based Diet Benefit Men’s Health Below the Belt?
MIAMI — A plant-based or plant-forward diet may offer some protection against prostate cancer and other sexual health issues, according to a systematic review. Twelve of the 23 studies that met the review’s inclusion criteria looked at prostate cancer, and data from large registry trials indicated a link between a plant-based diet and a decreased […]
Shorter Course of Radiation Therapy Proves Mettle in High-Risk Prostate Cancer
SAN ANTONIO — A shortened radiation therapy (RT) protocol for high-risk prostate cancer led to similar outcomes with no increase in toxicity compared with the standard treatment schedule, a randomized trial showed. Overall survival (OS) at 7 years was 82%, with no difference between standard RT and hypofractionation that reduced treatment duration from 8 to […]
High-Dose-Rate Brachytherapy Boost in Prostate Cancer Improves QOL
SAN ANTONIO — Men with intermediate- and high-risk prostate cancer treated with external-beam pelvic radiotherapy (EBRT) had better quality of life (QOL) outcomes when the combined prostate brachytherapy boost had a high dose rate (HDR), according to research presented here. In a randomized phase III trial comparing health-related QOL outcomes after either low dose rate […]