Nothing Lasts Forever, Including Infant BCG Vaccine Protection
Infants who received BCG [bacille Calmette-Guérin] vaccination at birth had protection against tuberculosis into early childhood, but that protection largely disappeared in only a few years, according to a meta-analysis. Effectiveness of the BCG vaccination against tuberculosis in all age groups was 18%. However, when the results were stratified by age, only in children younger […]
Durable Responses With IL-15 Superagonist in Early Bladder Cancer
The use of the IL-15RAFC superagonist N-803 with intravesical bacillus Calmette-Guérin (BCG) resulted in high and more durable response rates in patients with non-muscle invasive bladder cancer (NMIBC) carcinoma in situ who were unresponsive to BCG, a phase II/III study found. Of the 81 patients included in the analysis, 58 achieved a complete response at […]