Improved Survival With Surgery in Metastatic Breast Cancer
Selected patients with metastatic breast cancer at diagnosis had significantly better survival with surgery in addition to systemic therapy, an analysis of almost 13,000 patients showed. Overall, the survival hazard improved by 27%-36% in women with known receptor status (estrogen, progesterone, and HER2) treated with systemic therapy plus surgery with or without radiation therapy. Women […]
Molecular Changes Could Guide Metastatic Breast Cancer Therapy
Certain molecular changes in breast cancer genes occurred more often in metastatic disease, possibly suggesting new strategies for difficult-to-treat disease, according to initial data from an ongoing study. Matched tissue specimens from primary tumors and metastases showed higher rates of mutations in driver genes and variations in gene copy number in metastatic breast cancer (MBC). […]