Linaclotide Eases Abdominal Symptoms in IBS With Constipation
Linaclotide (Linzess) significantly alleviated abdominal symptoms in irritable bowel syndrome (IBS) patients with predominant constipation compared with placebo, researchers found in a randomized study. Using an abdominal score that averaged abdominal bloating, discomfort, and pain on an 11-point scale, the average overall change from baseline was -1.9 for patients treated with linaclotide and -1.2 for […]
Switching Twice With Infliximab Biosimilars Not Linked With IBD Flare Risk
LAS VEGAS — Biosimilar switching was not tied to flare in patients with inflammatory bowel disease (IBD), according to a retrospective cohort study. Patients who switched from infliximab (Remicade) to an infliximab biosimilar, and then switched again to a different biosimilar or back to infliximab, were no more or less likely to experience a disease […]
Red Meat Consumption Tied to Higher Chance of UC Flare
ORLANDO – For people with inflammatory bowel disease (IBD), that hamburger may come with more than just a side of fries — red meat consumption was linked with a higher risk for ulcerative colitis (UC) flare, researchers reported. According to an analysis of data from the IBD Partners research, patients with UC who were in […]
National Database Study Finds Higher Risk for Barrett’s Esophagus in IBD
ORLANDO – People with inflammatory bowel disease (IBD) faced higher odds of Barrett’s esophagus (BE) and BE without dysplasia, but not BE-linked malignancy, according to a cross-sectional study. Among patients diagnosed with ulcerative colitis (UC), the prevalence of BE was 0.077%, while the prevalence of BE in patients with Crohn’s disease (CD) came in at […]
Study suggests even more reasons to eat your fiber
Health professionals have long praised the benefits of insoluble fiber for bowel regularity and overall health. New research from the University of Minnesota suggests even more reasons we should be prioritizing fiber in our regular diets. In a new study published in Nutrients, researchers found that each plant source of insoluble fiber contains unique bioactives […]
Scientists link genes to diet in inflammatory bowel disease: A study in mice identifies candidate genes associated with bowel inflammation caused by a high-fat diet
A study of the genetic variation that makes mice more susceptible to bowel inflammation after a high-fat diet has identified candidate genes which may drive inflammatory bowel disease (IBD) in humans. The findings are published as a Reviewed Preprint in eLife. Described by the editors as a fundamental study, the work provides a framework for […]
Hyperbaric Oxygen Therapy Promising for Crohn’s Fistulas
DENVER — Hyperbaric oxygen therapy (HBOT) can help heal bowel fistulas in patients with advanced Crohn’s disease, according to a systematic review and meta-analysis. Overall, use of HBOT was associated with a 87% clinical response rate for all fistula subtypes, with more than half of the patients achieving clinical remission, or closure of the fistula […]
Wearable Tech Shows Promise for Predicting IBD Flares
DENVER — A smart watch app may help physicians and patients pinpoint and predict inflammatory bowel disease (IBD) flares, researchers reported. When a person with IBD has a normal gut environment, a bell curve is produced by the watch application, explained Robert Hirten, MD, of the Icahn School of Medicine/Susan and Leonard Feinstein Inflammatory Bowel […]
IBD Risk Higher After Antibiotics
Antibiotics were linked with increased risk for inflammatory bowel disease (IBD), especially among individuals 40 or older, in a population-based study conducted in Denmark. Of more than 6 million individuals followed for approximately 19 years, antibiotic use was associated with nearly 50% increased incidence of IBD in people ages 40 to 60 (IRR 1.48, 95% […]
Common food dye can trigger inflammatory bowel diseases, animal study suggests: Allura Red (also called FD&C Red 40 and Food Red 17), is a common ingredient in candies, soft drinks, dairy products and some cereals
Long-term consumption of Allura Red food dye can be a potential trigger of inflammatory bowel diseases (IBDs), Crohn’s disease and ulcerative colitis, says McMaster University’s Waliul Khan. Researchers using experimental animal models of IBD found that continual exposure to Allura Red AC harms gut health and promotes inflammation. The dye directly disrupts gut barrier function […]