SGLT2 Inhibitors, GLP-1 RAs Not Cost-Effective as First-Line T2D Agents
Although using newer classes of diabetes drugs as first-line therapy can boost life expectancy, this strategy can be quite pricey, according to a cost-effectiveness study. Compared with traditional first-line metformin, first-line SGLT2 inhibitors cost $43,000 more over a lifetime, and first-line GLP-1 receptor agonists cost $49,000 more, reported Neda Laiteerapong, MD, MS, of the University […]
Durvalumab-CRT Pairing Disappoints in Locally Advanced Cervical Cancer
NEW YORK — An immunotherapy-chemoradiotherapy (CRT) combination did not boost progression-free survival (PFS) in untreated, locally advanced cervical cancer, according to CALLA trial findings. Newly diagnosed patients who received durvalumab (Imfinzi) plus standard CRT did not experience a statistically significant PFS improvement versus patients who received placebo plus CRT (hazard ratio 0.84, 95% CI 0.65-1.08, […]
Routine Stress Testing Didn’t Offer Benefits to High-Risk Patients Post-PCI
BARCELONA – Routine functional testing after percutaneous cardiac interventions (PCI) did not boost clinical outcomes at 2 years in high-risk patients, according to the POST-PCI trial. The composite endpoint of death from any cause, myocardial infarction, or hospitalization for unstable angina was experienced by 5.5% of patients who got routine functional testing versus 6.6% in […]
More Evidence Hybrid Immunity Confers Highest Level of COVID Protection
Hybrid immunity from a COVID-19 infection plus a vaccine provided an immune boost against symptomatic disease, as well as severe outcomes, Brazilian researchers found. Among people who survived a COVID infection from Feb. 24, 2020 to Nov. 11, 2021, vaccine effectiveness against symptomatic disease at least 14 days after series completion was 44.0% (95% CI […]
Athletes warned against potential dangers of natural supplements
Nutritional supplements taken to boost athletic performance can pose risks to the heart, according to a European Society of Cardiology (ESC) statement published today in the European Journal of Preventive Cardiology, a journal of the ESC. “Nutritional supplements are commonly viewed as risk-free substances that may improve performance,” states the paper. “Some nutritional supplements, including […]
Benefits of Friendship: Why Do We Need a Friend in Our Life?
The benefits of friendship are endless. A good friend can help boost your mental and physical health, comfort you in times of need, and help reduce stress. Friendship is not just a subject that makes TV shows and movies more attractive, but it also adds immense vibrance to our lives. The true benefits of friendship cannot […]