Is Alzheimer’s Transmissible Through Bone Marrow Cells?
A mouse experiment suggested familial Alzheimer’s disease may be transmitted through bone marrow stem cells, but the implications of the findings were limited. The research involved transplanting bone marrow stem cells from mice engineered to carry a familial Alzheimer’s disease mutation into healthy mice, which led to “rapid development of Alzheimer’s disease pathological hallmarks,” reported […]
Opinion | Charting the Course: From Young Adult Leukemia Patient to Oncologist
Rosenthal is a lymphoma specialist. “Would you like to have a bone marrow biopsy today or tomorrow?” These are the only words I remember coming from the oncologist who I had just met in the emergency department (ED). I was in my second year of medical school and just 24 years old when I was […]
MRI-Guided Focused Ultrasound Eases Pain From Bone Metastases
MRI-guided focused ultrasound improved pain and quality of life for patients with bone metastases, similar to external beam radiation therapy (EBRT), according to a prospective nonrandomized phase II trial in Italy. At 1-month follow-up, the overall response rates were 91% for those who underwent focused ultrasound and 67% for those who underwent EBRT (P<0.001), with […]
For Men on ADT, Checking Bone Density May Thwart Fractures
Bone density testing in older prostate cancer patients on androgen deprivation therapy (ADT) was significantly associated with a decreased risk for major osteoporotic fractures, but remains little used, a prospective population-based study found. In the cohort of nearly 55,000 men treated with ADT from 2005 to 2015, those who received dual x-ray absorptiometry (DXA) screening […]
Immune cells produce chemical messenger that prevents heart disease–related inflammation
The immune system’s white blood cells, which are produced in the bone marrow, mostly help to defend against bacteria and injury, but sometimes they can turn against the body — for example, in cardiovascular disease, their inflammatory aggression can harm arteries and the heart. New research in Nature Immunology that was led by investigators at […]
Is Meningitis Contagious? How Long Does It Last?
Mastoiditis in children and adults is inflammation and/or infection of the mastoid bone, which is located behind the ear. The most common cause of mastoiditis is an inner ear infection or otitis media. Acute mastoiditis lasts for a short period, while chronic mastoiditis can last for months to years. Symptoms of acute mastoiditis in children […]
Men with high levels of body fat may be at risk for osteoporosis
Men with high levels of body fat have lower bone density and may be more likely to break a bone than those with normal levels of body fat, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism. Most studies have shown positive or neutral effects of body fat […]