Immunotherapy/BCG Combo Boosts EFS in Non-Muscle Invasive Bladder Cancer
LAS VEGAS — Event-free survival (EFS) in high-risk non-muscle invasive bladder cancer (NMIBC) improved significantly when patients received the PD-1 inhibitor sasanlimab in addition to bacillus Calmette-Guérin (BCG), a randomized trial showed. The 3-year EFS increased from 74.8% with standard-of-care BCG induction and maintenance to 82.1% with the addition of sasanlimab. Most of the improvement […]
Unprecedented Response Rates in Non-Responsive, Non-Muscle Invasive Bladder Cancer
LAS VEGAS — Patients with high-risk, treatment-unresponsive non-muscle invasive bladder cancer (NMIBC) had an unprecedented response rate and disease-free survival (DFS) with an investigational intravesical treatment system, data from an ongoing trial showed. Complete responses (CR) occurred in 82.4% of 85 patients treated with TAR-200, a system that delivers gemcitabine directly into the bladder. The […]
Do You Have Peeing Issues? These Foods And Drinks May Be To Blame.
Ekspansio via Getty Images The acid in citrus can exacerbate bladder symptoms. You’re likely familiar with foods that aren’t good for your heart. But when it comes to your bladder, it’s possible that you haven’t considered the correlation between diet and peeing. Unless you’ve had a urinary tract infection, suffered from a leaky bladder, or […]
Cancer Patients Face Frightening Delays in Treatment Approvals
Marine Corps veteran Ron Winters clearly recalls his doctor’s sobering assessment of his bladder cancer diagnosis in August 2022. “This is bad,” the 66-year-old Durant, Oklahoma, resident remembered his urologist saying. Winters braced for the fight of his life. Little did he anticipate, however, that he wouldn’t be waging war only against cancer. He also […]
Do You Have Peeing Issues? These Foods And Drinks May Be To Blame.
Ekspansio via Getty Images The acid in citrus can exacerbate bladder symptoms. You’re likely familiar with foods that aren’t good for your heart. But when it comes to your bladder, it’s possible that you haven’t considered the correlation between diet and peeing. Unless you’ve had a urinary tract infection, suffered from a leaky bladder, or […]
FDA Approves New First-Line Standard of Care in Bladder Cancer
Patients with locally advanced or metastatic bladder cancer have a permanent new first-line standard of care after the FDA granted full approval to the combination of enfortumab vedotin (Padcev) and pembrolizumab (Keytruda) regardless of cisplatin eligibility. The action finalized the approval process for the combination, which received accelerated approval earlier this year, at the time […]
Bladder-Sparing Neoadjuvant Protocol Gets High Marks for MIBC
More than 40% of patients with muscle-invasive bladder cancer (MIBC) avoided immediate cystectomy after achieving a clinical complete response (cCR) with a chemoimmunotherapy combination, a prospective study showed. Overall, 33 of 76 patients with MIBC achieved a cCR by stringently defined criteria following transurethral resection of bladder tumor (TURBT) and treatment with gemcitabine, cisplatin, and […]
Do You Have Peeing Issues? These Foods And Drinks May Be To Blame.
Ekspansio via Getty Images The acid in citrus can exacerbate bladder symptoms. You’re likely familiar with foods that aren’t good for your heart. But when it comes to your bladder, it’s possible that you haven’t considered the correlation between diet and peeing. Unless you’ve had a urinary tract infection, suffered from a leaky bladder, or […]
Agent Orange Exposure Tied to Bladder Cancer Risk in Veterans
Exposure to Agent Orange was associated with a modestly increased risk of bladder cancer among Vietnam War veterans, according to a retrospective cohort study. Among over 2.5 million male veterans, exposure to Agent Orange was associated with a relative 4% higher risk of bladder cancer (HR 1.04, 95% CI 1.02-1.06, P<0.001), reported Stephen Williams, MD, […]
Overactive Bladder Linked to Multiple Unmet Socioeconomic Needs
Unmet socioeconomic needs had a significant association with overactive bladder (OAB), adding to evidence of a complex interaction between social determinants of health and OAB, researchers said. Stressors such as housing and food insecurity and concerns about personal health as much as tripled the odds of reported OAB symptoms. The stressors remained significant predictors for […]