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Both high-protein and normal-protein diets are effective for T2D management

New findings from the University of Alabama at Birmingham indicate that the type of protein in the diet is not as important as the overall amount of weight loss for those with Type 2 diabetes. Published in the journal Obesity, 106 adults with T2D were randomly assigned to either the high-protein or normal-protein diet for […]

The Alabama Doc Who Sounded the Alarm on Unusual Hepatitis in Kids

On a mid-October day in Birmingham, Alabama, Markus Buchfellner, MD, examined a young child admitted to Children’s of Alabama with symptoms of vomiting, diarrhea and, most notably, a severe case of jaundice. It was the first in a series of mysterious cases that would lead to a CDC investigation. “These kids just looked yellow; eyes, […]

A novel therapy ameliorates obesity and Type 2 diabetes in mice fed a high-fat diet: This therapy, using sustained release of nitric oxide, may be a novel, efficient and safe way to prevent and treat multiple metabolic diseases.

A novel therapy developed at the University of Alabama at Birmingham ameliorates obesity and Type 2 diabetes in mice fed a high-fat diet. The therapy acts through sustained release of nitric oxide, a gaseous signaling chemical whose most important function in the body is relaxing the inner muscles of blood vessels. “Because reduced bioavailability of […]

A microRNA network is the putative mediator of reductive stress in the heart: Understanding how reductive stress is controlled may help personalize treatment of heart failure patients, leading to better outcomes

Last year, University of Alabama at Birmingham researchers reported that reductive stress — an imbalance in the normal oxidation/reduction homeostasis — caused pathological changes associated with heart failure in a mouse model. This was a follow-up to their 2018 clinical study that about one in six heart failure patients shows reductive stress. Now, in the […]

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