Skin Test Detects Parkinson’s and Other Synucleinopathies
Skin biopsies detected phosphorylated alpha-synuclein in a high proportion of people with Parkinson’s disease and other synucleinopathies. Finding a reliable diagnostic biomarker for synucleinopathies is an urgent unmet need. Further research is needed in other clinical populations to validate these findings. Skin biopsies detected cutaneous phosphorylated alpha-synuclein (p-syn) in a high proportion of people who […]
Short-Course Apalutamide to Reduce Active Surveillance Attrition in Prostate Cancer
A majority of men in active surveillance (AS) for early prostate cancer had negative biopsies after a 90-day course of apalutamide (Erleada), a small phase II trial showed. Follow-up pathology showed no evidence of residual cancer in 13 of 22 evaluable patients following treatment with the androgen receptor inhibitor. The median time to a positive […]