Linezolid ‘Not Recommended’ to Treat Early Syphilis
Linezolid failed to meet noninferiority criteria when compared with standard benzathine penicillin G (BPG) in the treatment of early syphilis, according to findings of the randomized, controlled Trep-AB Study of cisgender men. Only 70% of trial participants with early syphilis who were treated with linezolid were cured, compared with 100% of participants treated with penicillin, […]
Single Dose of Antibiotic Cured Early Syphilis, Even in Those With HIV
BOSTON — One dose of benzathine penicillin G for the treatment of early syphilis was shown to be noninferior to a regimen of three weekly doses a week apart, even among people who are living with HIV, a randomized trial showed. At 6 months among patients with and without HIV, the cumulative response was 76% […]