Targeted Combo Flops as First-Line Treatment in Advanced Breast Cancer
PARIS — A novel combination failed to improve the clinical benefit rate (CBR) in advanced triple-negative breast cancer (TNBC) compared with chemoimmunotherapy, a randomized trial showed. Adding the anti-CD73 antibody oleclumab to durvalumab (Imfinzi) and chemotherapy led to clinical benefit (response plus stable disease) in 43% of patients by 24 weeks as compared with 44% […]
10-Year Follow-Up Confirms Benefit of Chemoradiotherapy in MIBC Patients
Long-term results confirmed that the benefit of adding chemotherapy to radiotherapy was maintained in patients with muscle-invasive bladder cancer (MIBC) in a follow-up to the phase III randomized BC2001 trial. Over a median follow-up of about 10 years, locoregional control was significantly improved by adding 5-fluorouracil and mitomycin C to radiotherapy, with a 5-year recurrence-free […]
New Study Reveals The Ages When Drinking May Be The Most Damaging
Iuliia Bondar via Getty ImagesNew research indicates there’s zero benefit to consuming alcohol when you’re younger. In fact, it could pose a huge risk. If you’re under the age of 40, a new study suggests you might want to stop drinking. Altogether. The consumption of alcohol holds significant health risks and no benefits for young […]
When AI is the inventor who gets the patent?
The day is coming — some say has already arrived — when new inventions that benefit society are dreamt up by artificial intelligence all on its own. It’s not surprising these days to see new inventions that either incorporate or have benefitted from artificial intelligence (AI) in some way, but what about inventions dreamt up […]
PBMs Under Fire at Senate Hearing
The role of pharmacy benefit managers (PBMs) in the drug supply chain and whether “anti-competitive” practices are driving up healthcare costs was scrutinized by the Senate on Thursday. PBMs are just one player in a “broken supply chain” explained Richard Blumenthal (D-Conn.), during a Thursday hearing of the Senate Subcommittee for the Committee on Commerce, […]
Automated nutrition app can help people follow healthier diet
People could benefit from fully automated personal nutritional advice, as a new research paper shows that an app improved healthy diet in clinical trials. A paper published in the Journal of Medical Internet Research today (Mon 25 April 22) shows how the eNutri app developed by researchers in human nutrition and biomedical engineering at the […]
Experimental drug boosts immunotherapy effectiveness in pancreatic cancer in mice
An experimental drug enhanced the benefit of an immunotherapy to fight pancreatic cancer in mice by increasing the number of immune cells in the immediate vicinity of the tumor, leading to a reduction in tumor growth, and in some mice, eliminating their cancer. The findings, from researchers at Georgetown Lombardi Comprehensive Cancer Center and BioXcel […]
Elephants benefit from having older siblings, especially sisters
A study of semi-captive Asian elephants in Myanmar has found that calves benefit from having older sisters more than older brothers. The findings are published in the British Ecological Society’s Journal of Animal Ecology. Researchers at universities in Finland, the UK and Myanmar have found that Asian elephant siblings influence younger offspring from early through […]
Plant-Based Diet Tied to Better Urological Health in Men
Men interested in preserving their urological health may benefit from eating more vegetables and fruits, researchers reported. A trio of studies presented at the American Urological Society (AUA) virtual meeting suggested that plant-based diets were associated with a decreased risk of erectile dysfunction (ED), lower PSA rates, and possibly a lower rate of total and […]
New Study Finds Yet Another Health Benefit Of The COVID Vaccine
Getting the coronavirus vaccine provides one obvious and significant health benefit: It protects you from getting seriously sick or dying if you come into contact with the virus. That, in itself, is amazing. But new research published on Wednesday points to another striking benefit of rolling up your sleeves that should not be dismissed: People […]