Brain Structure, Widespread Connectivity Changes Seen With Long COVID
Gray matter atrophy and severe disruption of brain functional connectivity were seen in long COVID patients with anxiety and depression about 3 months after acute mild SARS-CoV-2 infection. Compared with people who were asymptomatic after SARS-CoV-2 infection, long COVID patients with both anxiety and depression showed limbic atrophy and a widespread pattern of hyperconnectivity, reported […]
FDA Approves First Treatment for Geographic Atrophy Secondary to AMD
The FDA approved pegcetacoplan injection (Syfovre) as the first treatment for geographic atrophy (GA) secondary to age-related macular degeneration (AMD), according to a statement from Apellis Pharmaceuticals. Primary support for the approval came from the randomized, sham-controlled DERBY and OAKS trials, which showed a 22% overall reduction in growth of GA with pegcetacoplan over 24 […]
Cervical Cord Atrophy Predicts Silent MS Progression
Spinal cord atrophy predicted disease progression in people with relapsing multiple sclerosis (MS), a single-center observational study showed. A 1% faster cervical cord atrophy rate was associated with 69% (P<0.0001) shorter time to silent clinical progression and a 53% (P<0.0001) shorter time to secondary progressive MS (SPMS) conversion, reported Antje Bischof, MD, of University Hospital […]