Pediatric Allergic March Supported by Nationwide EHR Data
A typical allergic march started with atopic dermatitis during infancy and progressed to other allergies later in life, a multi-state study found. In total, 13.4% of pediatric study participants had two or more allergic conditions based on electronic health record (EHR) information, reported David A. Hill, MD, PhD, of Children’s Hospital of Philadelphia, and coauthors. […]
Durable Responses, Safety in Atopic Dermatitis Treated With IL-13 Inhibitor
The interleukin (IL)-13 inhibitor tralokinumab (Adbry) for atopic dermatitis provided long-term disease control with a favorable safety profile and improved quality of life (QoL), data from two studies showed. Interim results from a long-term extension study showed that 82.5% of patients had at least 75% improvement in the Eczema Area and Severity Index (EASI-75) after […]
Onset of Allergies including asthma and hay fever not directly causally linked to mental health traits
Allergic diseases such as asthma, atopic dermatitis and hay fever do not cause the onset of mental health conditions or vice versa, according to the findings of a new University of Bristol-led study published today (6 October) in the journal Clinical and Experimental Allergy. While previous studies have reported an observational relationship between mental health and […]
Oral Drug Active in Teens With Atopic Dermatitis
Teenagers with moderate or severe atopic dermatitis (AD) had significant improvement at 12 weeks with the investigational oral Janus kinase (JAK) inhibitor abrocitinib plus topical therapy, a placebo-controlled trial showed. Almost half of the patients had clear or almost clear skin by clinician assessment (IGA), and about 70% of patients treated with either of two […]
Clinical Challenges: Managing Mental Health in Eczema Patients
Adults with atopic dermatitis (AD) carried a higher burden of disease than those with other chronic diseases, such as cardiovascular disease, diabetes, and hypertension, a U.S. study showed. Even patients with mild AD can experience a “profound” disease burden that significantly impairs quality of life (QoL), putting them at increased risk of anxiety, depression, and […]